Solaro C, Brichetto G, Amato M P, Cocco E, Colombo B, D'Aleo G, Gasperini C, Ghezzi A, Martinelli V, Milanese C, Patti F, Trojano M, Verdun E, Mancardi G L
Department of Neurology, P.A. Micone Hospital, Genova, Italy.
Neurology. 2004 Sep 14;63(5):919-21. doi: 10.1212/01.wnl.0000137047.85868.d6.
In a multicenter cross-sectional study, the authors assessed pain in patients with multiple sclerosis (MS) using a symptom-oriented approach. Out of 2,077 questionnaires, we used 1,672 for data analysis. Pain and frequencies included trigeminal neuralgia 2%, Lhermitte's sign 9%, dysesthetic pain 18.1%, back pain 16.4%, and painful tonic spasms 11%. Comparison between different groups showed significant differences for age, Expanded Disability Status Scale, disease duration, and disease course, but not for sex. This study underlines the relevance of pain in the clinical history of MS.
在一项多中心横断面研究中，作者采用以症状为导向的方法评估了多发性硬化症（MS）患者的疼痛情况。在2077份问卷中，我们使用了1672份进行数据分析。疼痛类型及发生率包括：三叉神经痛2%、莱尔米特征9%、感觉异常性疼痛18.1%、背痛16.4%以及痛性强直性痉挛11%。不同组之间的比较显示，在年龄、扩展残疾状态量表、病程和疾病进程方面存在显著差异，但在性别方面无显著差异。这项研究强调了疼痛在MS临床病史中的相关性。
