Ashfaq R, Timmons C F
Department of Pathology, University of Texas Southwestern Medical Center, Dallas.
Arch Pathol Lab Med. 1992 Mar;116(3):299-301.
A 9-year-old boy with a large mass in the right lower quadrant of the abdomen was diagnosed as having disseminated Burkitt's lymphoma by pleural fluid aspirate. After 4 months of chemotherapy, he developed acute small-bowel obstruction. A resected ileal segment contained a bright-yellow annular submucosal tumor, histologically a xanthoma, that infiltrated the muscularis propria and serosa. No residual lymphoma was identified. We believe that the small-bowel xanthoma in this child is an unusual, nonneoplastic, treatment-related sequela of lymphoma cell lysis and histiocytic scavenging of lipid-membranous debris.
一名9岁男孩，右下腹部有一巨大肿块，经胸腔积液抽吸诊断为播散性伯基特淋巴瘤。化疗4个月后，他出现急性小肠梗阻。切除的一段回肠中有一个亮黄色环形黏膜下肿瘤，组织学检查为黄色瘤，肿瘤浸润固有肌层和浆膜层。未发现残留淋巴瘤。我们认为，该患儿的小肠黄色瘤是淋巴瘤细胞溶解及组织细胞清除脂质膜碎片所致的一种罕见的、非肿瘤性的、与治疗相关的后遗症。
