• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

化疗后出现的良性富含组织细胞的假瘤并酷似残留病灶。

Benign Histiocyte-Rich Pseudotumor Developing Postchemotherapy and Mimicking Residual Disease.

作者信息

Singh Amrit P, Murray Glenn P, Pandey Soumya

机构信息

Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.

出版信息

Case Rep Pathol. 2020 Jul 2;2020:4674103. doi: 10.1155/2020/4674103. eCollection 2020.

DOI:10.1155/2020/4674103
PMID:32695545
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7352137/
Abstract

Histiocyte-rich pseudotumors (HRPT) developing postchemoradiation therapy are a florid response to treatment and reparative change. Although these are benign processes, clinically and radiologically, these may mimic recurrent/relapsed disease. We describe a case of an adult male with history of diffuse large B-cell lymphoma (DLBCL), status postchemoradiation therapy, who developed HRPT at the site of original involvement, mimicking relapse of disease on positron emission tomography/computed tomography (PET/CT) imaging. This is one of the few reported cases of posttreatment HRPT. This entity is important to point out the limitations of PET/CT imaging in patients with lymphomas and metastatic disease and stresses the importance of an excisional biopsy for determining relapse and the need for further treatment.

摘要

放化疗后出现的富含组织细胞的假瘤（HRPT）是对治疗的一种显著反应及修复性改变。尽管这些是良性过程，但在临床和放射学上，它们可能酷似复发/再发疾病。我们描述了一例成年男性，有弥漫性大B细胞淋巴瘤（DLBCL）病史，放化疗后，在原受累部位出现HRPT，在正电子发射断层扫描/计算机断层扫描（PET/CT）成像上酷似疾病复发。这是为数不多的报道的治疗后HRPT病例之一。指出这个实体对于明确PET/CT成像在淋巴瘤和转移性疾病患者中的局限性很重要，并强调了切除活检对于确定复发及进一步治疗需求的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46ec/7352137/a0dd3ab75fb2/CRIPA2020-4674103.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46ec/7352137/fa7a4d775d5e/CRIPA2020-4674103.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46ec/7352137/ecfcf4a692ac/CRIPA2020-4674103.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46ec/7352137/a0dd3ab75fb2/CRIPA2020-4674103.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46ec/7352137/fa7a4d775d5e/CRIPA2020-4674103.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46ec/7352137/ecfcf4a692ac/CRIPA2020-4674103.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46ec/7352137/a0dd3ab75fb2/CRIPA2020-4674103.003.jpg

相似文献

1
Benign Histiocyte-Rich Pseudotumor Developing Postchemotherapy and Mimicking Residual Disease.化疗后出现的良性富含组织细胞的假瘤并酷似残留病灶。
Case Rep Pathol. 2020 Jul 2;2020:4674103. doi: 10.1155/2020/4674103. eCollection 2020.
2
Histiocyte-rich xanthomatous pseudotumor mimicking relapse on positron emission tomography imaging in an adolescent with primary mediastinal diffuse large B-cell lymphoma.在一名患有原发性纵隔弥漫性大B细胞淋巴瘤的青少年中，富含组织细胞的黄色瘤样假瘤在正电子发射断层扫描成像上酷似复发。
J Pediatr Hematol Oncol. 2012 Apr;34(3):232-5. doi: 10.1097/MPH.0b013e3182281c54.
3
Postchemotherapy Histiocyte-rich Pseudotumor Mimicking Residual Lymphoma: A Report of 11 Cases Correlating Clinicopathologic and Radiologic Findings.化疗后富含组织细胞的假性肿瘤样增生：11 例病例的临床病理和影像学表现相关性报告。
Am J Surg Pathol. 2021 Feb 1;45(2):160-168. doi: 10.1097/PAS.0000000000001547.
4
Benign histiocyte-rich pseudotumor in post treatment mediastinal Hodgkin's lymphoma.治疗后纵隔霍奇金淋巴瘤中的富含良性组织细胞的假瘤
Radiol Case Rep. 2019 Nov 28;15(2):156-160. doi: 10.1016/j.radcr.2019.10.018. eCollection 2020 Feb.
5
Postchemotherapy histiocyte-rich pseudotumor involving the spleen.
Am J Clin Pathol. 2009 Sep;132(3):342-8. doi: 10.1309/AJCPC67QOGJXCEZB.
6
Utility of Bone Marrow Biopsy and Aspirate for Staging of Diffuse Large B Cell Lymphoma in the Era of Positron Emission Tomography With 2-Deoxy-2-[Fluorine-18]fluoro-deoxyglucose Integrated With Computed Tomography.在正电子发射断层扫描与2-脱氧-2-[氟-18]氟脱氧葡萄糖联合计算机断层扫描时代，骨髓活检和抽吸在弥漫性大B细胞淋巴瘤分期中的应用
Clin Lymphoma Myeloma Leuk. 2017 Oct;17(10):631-636. doi: 10.1016/j.clml.2017.06.010. Epub 2017 Jun 17.
7
Postchemotherapy Histiocyte-Rich Pseudotumor of the Spleen Simulating Residual Disease in a Patient With Non-Hodgkin Lymphoma on FDG PET/CT.氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描示化疗后富组织细胞假性肿瘤酷似非霍奇金淋巴瘤残留病灶
Clin Nucl Med. 2019 Jun;44(6):e409-e412. doi: 10.1097/RLU.0000000000002568.
8
Post-Chemotherapy Histiocyte-Rich Pseudotumors: Radiologic and Endoscopic Mimics of Residual Lymphoma.化疗后富含组织细胞的假瘤：残留淋巴瘤的放射学和内镜模拟物
Acta Haematol. 2022;145(1):18-29. doi: 10.1159/000517181. Epub 2021 Jul 20.
9
Among diffuse large B-cell lymphomas, T-cell-rich/histiocyte-rich BCL and CD30+ anaplastic B-cell subtypes exhibit distinct clinical features.在弥漫性大B细胞淋巴瘤中，富含T细胞/组织细胞的大B细胞淋巴瘤和CD30+间变性B细胞亚型表现出不同的临床特征。
Ann Oncol. 2001 Jun;12(6):853-8. doi: 10.1023/a:1011195708834.
10
Use of FDG PET/CT in identification of bone marrow involvement in diffuse large B cell lymphoma and follicular lymphoma: comparison with iliac crest bone marrow biopsy.氟代脱氧葡萄糖正电子发射断层扫描/计算机断层扫描（FDG PET/CT）在识别弥漫性大B细胞淋巴瘤和滤泡性淋巴瘤骨髓受累中的应用：与髂嵴骨髓活检的比较
Acta Radiol. 2017 Dec;58(12):1476-1484. doi: 10.1177/0284185117701305. Epub 2017 Apr 6.

引用本文的文献

1
Ileal inflammatory pseudotumor in adolescent male patient with prior Burkitt lymphoma: A challenging diagnosis.患有既往伯基特淋巴瘤的青春期男性患者的回肠炎性假瘤：一项具有挑战性的诊断。
Radiol Case Rep. 2021 Jun 8;16(8):2047-2052. doi: 10.1016/j.radcr.2021.04.082. eCollection 2021 Aug.

本文引用的文献

1
Histiocytic Sarcoma: Review, Discussion of Transformation From B-Cell Lymphoma, and Differential Diagnosis.组织细胞肉瘤：综述、与 B 细胞淋巴瘤转化的讨论及鉴别诊断。
Arch Pathol Lab Med. 2018 Nov;142(11):1322-1329. doi: 10.5858/arpa.2018-0220-RA.
2
A Review of Gaucher Disease Pathophysiology, Clinical Presentation and Treatments.戈谢病的病理生理学、临床表现及治疗综述
Int J Mol Sci. 2017 Feb 17;18(2):441. doi: 10.3390/ijms18020441.
3
Xanthogranuloma in the heavily irradiated low neck in a patient with head and neck cancer.一名头颈癌患者颈部重度放疗区域出现的黄色肉芽肿。
J Otolaryngol Head Neck Surg. 2016 Mar 24;45:20. doi: 10.1186/s40463-016-0134-6.
4
Inflammatory pseudotumor-like follicular dendritic cell tumor of liver and spleen: granulomatous and eosinophil-rich variants mimicking inflammatory or infective lesions.肝脾炎性假瘤样滤泡树突细胞肿瘤：伴肉芽肿和嗜酸性粒细胞增多的变体，类似于炎症或感染性病变。
Am J Surg Pathol. 2014 May;38(5):646-53. doi: 10.1097/PAS.0000000000000170.
5
Histiocyte-rich xanthomatous pseudotumor mimicking relapse on positron emission tomography imaging in an adolescent with primary mediastinal diffuse large B-cell lymphoma.在一名患有原发性纵隔弥漫性大B细胞淋巴瘤的青少年中，富含组织细胞的黄色瘤样假瘤在正电子发射断层扫描成像上酷似复发。
J Pediatr Hematol Oncol. 2012 Apr;34(3):232-5. doi: 10.1097/MPH.0b013e3182281c54.
6
Adverse events associated with concurrent chemoradiation therapy in patients with head and neck cancer.头颈部癌患者同步放化疗相关的不良事件。
Arch Otolaryngol Head Neck Surg. 2009 Dec;135(12):1209-17. doi: 10.1001/archoto.2009.174.
7
Postchemotherapy histiocyte-rich pseudotumor involving the spleen.
Am J Clin Pathol. 2009 Sep;132(3):342-8. doi: 10.1309/AJCPC67QOGJXCEZB.
8
Overview of lymphoma diagnosis and management.淋巴瘤的诊断与管理概述。
Radiol Clin North Am. 2008 Mar;46(2):175-98, vii. doi: 10.1016/j.rcl.2008.03.005.
9
Inflammatory myofibroblastic tumours: where are we now?炎性肌纤维母细胞瘤：我们目前的进展如何？
J Clin Pathol. 2008 Apr;61(4):428-37. doi: 10.1136/jcp.2007.049387. Epub 2007 Oct 15.
10
Inflammatory myofibroblastic tumor: comparison of clinicopathologic, histologic, and immunohistochemical features including ALK expression in atypical and aggressive cases.炎性肌成纤维细胞瘤：非典型及侵袭性病例的临床病理、组织学和免疫组化特征比较，包括ALK表达情况
Am J Surg Pathol. 2007 Apr;31(4):509-20. doi: 10.1097/01.pas.0000213393.57322.c7.