Erickson Steven R, Thomas Linda A, Blitz Susan G, Pontius Lindsey R
College of Pharmacy, University of Michigan, Ann Arbor, MI, USA.
Ann Pharmacother. 2004 Nov;38(11):1805-10. doi: 10.1345/aph.1E194. Epub 2004 Sep 14.
Most patients attempting to quit smoking experience symptoms that may influence functioning and sense of well-being.
To conduct a pilot study to assess the acute effects of smoking cessation on health-related quality of life (HRQoL) and perceived work performance.
Questionnaires were mailed to patients of a smoking-cessation program just prior to quit date and one week after they quit. The questionnaires included the Smoking Cessation Quality of Life Questionnaire and the Work Performance Scale (WPS). Other data included patient demographics, smoking duration, Fagerstro m Test for Nicotine Dependence scale, and smoking status. Student's t-tests were used for pre-post comparisons as well as comparison between higher addiction and lower addiction groups, with p </= 0.05 used for determination of statistical significance.
Thirty-four respondents (higher addiction = 12, lower addiction = 22) averaged 48.6 +/- 12.0 (mean +/- SD) years of age and were primarily white (97.1%) and female (72.2%). From baseline to one week post-quit, there was significant worsening of anxiety (71.5 +/- 25.1 to 61.1 +/- 26.0; p = 0.04) and cognitive functioning (72.2 +/- 20.4 to 61.3 +/- 23.9; p = 0.02) scores and improved general health (65.2 +/- 18.4 to 70.5 +/- 16.9; p = 0.01). HRQoL scores for the lower addiction group were higher than those for the higher addiction group, significantly for sleep, cognitive functioning, anxiety, role emotional and mental health. Both groups experienced significant improvement in self-control. The lower addiction group had a significant decline in sleep, cognitive function, and anxiety, while only one domain changed significantly for the higher addiction group. There were no significant differences in WPS analyses.
This pilot study found that, generally, HRQoL changes one week into a smoking cessation attempt. Smokers with higher addiction have lower HRQoL when they begin their cessation attempt, while smokers with lower addiction have greater change in HRQoL.
大多数试图戒烟的患者会经历一些可能影响其功能和幸福感的症状。
开展一项试点研究,以评估戒烟对健康相关生活质量(HRQoL)和感知工作表现的急性影响。
在戒烟日期前和戒烟一周后,向一个戒烟项目的患者邮寄问卷。问卷包括《戒烟生活质量问卷》和《工作表现量表》(WPS)。其他数据包括患者人口统计学信息、吸烟时长、尼古丁依赖程度的法格斯特罗姆测试量表以及吸烟状况。采用学生t检验进行前后比较以及高成瘾组和低成瘾组之间的比较,p≤0.05用于确定统计学显著性。
34名受访者(高成瘾组 = 12人,低成瘾组 = 22人)平均年龄为48.6±12.0岁(均值±标准差),主要为白人(97.1%)且女性占多数(72.2%)。从基线到戒烟后一周,焦虑得分(71.5±25.1降至61.1±26.0;p = 0.04)和认知功能得分(72.2±20.4降至61.3±23.9;p = 0.02)显著恶化,总体健康状况得到改善(65.2±18.4升至70.5±16.9;p = 0.01)。低成瘾组的HRQoL得分高于高成瘾组,在睡眠、认知功能、焦虑、角色情感和心理健康方面差异显著。两组的自我控制能力均有显著改善。低成瘾组的睡眠、认知功能和焦虑显著下降,而高成瘾组只有一个领域有显著变化。WPS分析无显著差异。
这项试点研究发现,一般来说,在戒烟尝试一周时HRQoL会发生变化。成瘾程度较高的吸烟者在开始戒烟尝试时HRQoL较低,而成瘾程度较低的吸烟者HRQoL变化更大。