Croghan Ivana T, Schroeder Darrell R, Hays J Taylor, Eberman Kay M, Patten Christi A, Berg Emily J, Hurt Richard D
Nicotine Research Program, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA.
Eur J Public Health. 2005 Jun;15(3):251-5. doi: 10.1093/eurpub/cki076. Epub 2005 May 19.
This study evaluated change in health status as a function of change in smoking status among patients treated clinically for nicotine dependence by comparing overall perceived health status of patients who abstained from cigarettes for 1 year versus those who smoked continuously for 1 year.
Patients from the Mayo Clinic Nicotine Dependence Center completed a quality-of-life questionnaire (SF-36) following their consultation for nicotine dependence (baseline). At 1 year post-intervention, patients were mailed a follow-up survey that included the SF-36 and items assessing interval smoking history. Study patients included those who self-reported continuous smoking (n=60) and those reporting continuous smoking abstinence for the entire follow-up year (n=146). Data from SF-36 scales at 1 year were analysed using analysis of covariance with baseline scale scores serving as covariates along with baseline characteristics that differed significantly between groups.
Compared with those who continued to smoke, patients who were continuously abstinent from smoking for the entire year had more improvement in perceived health status for the SF-36 mental composite scale (P=0.009) and for the SF-36 subscales for role limitations (P<0.001 and P=0.017 for emotional and physical role limitations, respectively), social functioning (P=0.010) and general health (P=0.013).
Smokers treated for nicotine dependence who stop smoking for a year report more improvement in-quality-of-life compared with those who continue to smoke.
本研究通过比较戒烟1年的患者与持续吸烟1年的患者的总体健康状况感知，评估了临床治疗尼古丁依赖患者的健康状况变化与吸烟状况变化之间的关系。
梅奥诊所尼古丁依赖中心的患者在咨询尼古丁依赖问题后（基线）完成了一份生活质量问卷（SF - 36）。在干预后1年，向患者邮寄了一份随访调查问卷，其中包括SF - 36以及评估期间吸烟史的项目。研究患者包括自我报告持续吸烟的患者（n = 60）和报告在整个随访年度持续戒烟的患者（n = 146）。使用协方差分析对1年时SF - 36量表的数据进行分析，将基线量表得分作为协变量，并结合两组之间有显著差异的基线特征。
与继续吸烟的患者相比，全年持续戒烟的患者在SF - 36心理综合量表的健康状况感知方面有更大改善（P = 0.009），在SF - 36角色限制子量表方面（情感和身体角色限制分别为P < 0.001和P = 0.017）、社会功能（P = 0.010）和总体健康（P = 0.013）方面也有更大改善。
接受尼古丁依赖治疗的吸烟者中，戒烟一年的患者比继续吸烟的患者报告生活质量改善更大。
