Gorelick Philip B
Department of Neurology and Rehabilitation, University of Illinois College of Medicine at Chicago, 912 South Wood St, Room 855N, Chicago, IL 60612, USA.
Stroke. 2004 Nov;35(11 Suppl 1):2620-2. doi: 10.1161/01.STR.0000143318.70292.47. Epub 2004 Sep 16.
Alzheimer disease and vascular cognitive impairment are important causes of cognitive decline in the elderly. It has now been shown that vascular risk factors have measurable negative effects on the brain and are associated with cognitive impairment. We review vascular factors that might be responsible to cognitive decline in Alzheimer disease and vascular cognitive impairment and the corresponding interventions that might prevent cognitive impairment as we age.
阿尔茨海默病和血管性认知障碍是老年人认知能力下降的重要原因。现已表明,血管危险因素对大脑有可测量的负面影响,并与认知障碍相关。我们综述了可能导致阿尔茨海默病和血管性认知障碍认知能力下降的血管因素,以及随着年龄增长可能预防认知障碍的相应干预措施。