Bowler J V
Department of Clinical Neurosciences, Royal Free & University College Medical School, Hampstead Campus, Rowland Hill St., London NW3 2PF, UK.
Br Med Bull. 2007;83:291-305. doi: 10.1093/bmb/ldm021. Epub 2007 Aug 4.
Vascular cognitive impairment (VCI) has superseded vascular dementia and multi-infarct dementia as the concept to be used in cognitive decline due to cerebrovascular disease.
The literature was reviewed with regard to the concept of VCI and its incidence, pathophysiological substrate, clinical features and management.
A change in the diagnostic paradigm from the current Alzheimer-based definition of vascular dementia to VCI will allow the earlier identification of cases and will identify a different population from that recognized using the current criteria for vascular dementia.
Case identification at the earliest possible stage affords the greatest opportunity for treatment that may slow the rate of progression.
血管性认知障碍（VCI）已取代血管性痴呆和多发梗死性痴呆，成为用于描述脑血管疾病所致认知功能下降的概念。
对有关VCI的概念、发病率、病理生理基础、临床特征及管理的文献进行综述。
诊断模式从当前基于阿尔茨海默病的血管性痴呆定义转变为VCI，将有助于更早地识别病例，并识别出与使用当前血管性痴呆标准所识别的不同人群。
尽早识别病例为进行可能减缓疾病进展速度的治疗提供了最大机会。
