Müller-Stöver I, Richter J, Häussinger D
Tropenmedizinische Ambulanz der Klinik für Gastroenterologie, Hepatologie und Infektologie, Universität Düsseldorf, Düsseldorf.
Dtsch Med Wochenschr. 2004 Sep 17;129(38):1973-5. doi: 10.1055/s-2004-831835.
A 63-year-old man, who had travelled extensively in Asia and had lived in South Africa, presented with increasing dysphagia. Physical examination showed no abnormalities.
Upper gastrointestinal endoscopy showed a concentric oesophageal stenosis, 5 cm long, consisting of thickening of the wall without any sign of malignancy or mucocutaneous lesions. The histological examination of this lesion demonstrated infiltrations of eosinophilic cells. Serology was positive for Gnathostoma spinigerum.
After treatment with albendazole 400 mg per day for 3 weeks the clinical, histological and serological symptoms resolved completely.
In case of any eosinophilia or local infiltrations of eosinophilic cells, parasitic disease have to be considered.
一名63岁男性，曾在亚洲多地旅行并在南非居住，出现进行性吞咽困难。体格检查未发现异常。
上消化道内镜检查显示一处5厘米长的同心性食管狭窄，由管壁增厚构成，无任何恶性肿瘤迹象或黏膜皮肤病变。该病变的组织学检查显示嗜酸性细胞浸润。棘颚口线虫血清学检查呈阳性。
每天服用400毫克阿苯达唑治疗3周后，临床、组织学和血清学症状完全缓解。
出现任何嗜酸性粒细胞增多或嗜酸性细胞局部浸润的情况时，都必须考虑寄生虫病。
