Panizza J A, Finucane K E
Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, Nedlands, Western Australia.
J Appl Physiol (1985). 1992 Jan;72(1):231-5. doi: 10.1152/jappl.1992.72.1.231.
Pleural pressure is usually estimated with a balloon catheter (BC) positioned in the middle third of the esophagus. An alternate method, which avoids potential inaccuracies associated with changes in balloon volume, is a catheter-mounted transducer (CMT) system. To assess the accuracy of a CMT system in defining the elastic properties of the lungs, we compared the static pressure-volume (PV) properties of the lungs measured sequentially with CMT and BC systems in six healthy subjects each on two occasions, relating static transpulmonary pressure (Pst,L) to lung volume during interrupted exhalations from total lung capacity (TLC). PV data were fitted with an exponential function (least-squares method), and the exponent (k) was used to define the shape of the PV curve; position was defined by Pst,L at TLC and at 90 and 60% TLC. These data were examined for agreement (paired t test) and repeatability (coefficient of repeatability). No significant differences were demonstrated: k was 0.10 +/- 0.02 and 0.11 +/- 0.03 (SD) and Pst,L at 60% TLC was 8.27 +/- 2.09 and 8.37 +/- 1.63 cmH2O for the CMT and BC systems, respectively. The coefficient of repeatability for each parameter was not significantly different but was consistently less with the BC, suggesting better repeatability. We conclude that a CMT system is an acceptable alternative to a BC system for defining the elastic properties of lungs.
胸膜压力通常通过置于食管中三分之一处的球囊导管(BC)进行估计。一种可避免与球囊容积变化相关潜在误差的替代方法是导管安装式换能器(CMT)系统。为评估CMT系统在定义肺弹性特性方面的准确性,我们在6名健康受试者中,分别在两个不同时间,依次用CMT系统和BC系统测量肺的静态压力-容积(PV)特性,将静态跨肺压(Pst,L)与从肺总量(TLC)进行间断呼气过程中的肺容积相关联。PV数据采用指数函数(最小二乘法)拟合,指数(k)用于定义PV曲线的形状;位置由TLC、90%TLC和60%TLC时的Pst,L确定。对这些数据进行一致性检验(配对t检验)和重复性检验(重复性系数)。未发现显著差异:CMT系统和BC系统的k分别为0.10±0.02和0.11±0.03(标准差),60%TLC时的Pst,L分别为8.27±2.09和8.37±1.63cmH2O。每个参数的重复性系数无显著差异,但BC系统的始终较小,表明重复性更好。我们得出结论,CMT系统是用于定义肺弹性特性的BC系统的可接受替代方法。