VenUS I的经济学分析，一项关于两种绷带治疗下肢静脉溃疡的随机试验。

Economic analysis of VenUS I, a randomized trial of two bandages for treating venous leg ulcers.

作者信息

Iglesias C P, Nelson E A, Cullum N, Torgerson D J

机构信息

Department of Health Sciences, Seebohm Rowntree Building (Area 4), University of York, Heslington, York YO10 5DD, UK.

出版信息

Br J Surg. 2004 Oct;91(10):1300-6. doi: 10.1002/bjs.4755.

DOI:10.1002/bjs.4755

PMID:15382101

Abstract

BACKGROUND

The study investigated the cost-effectiveness of four-layer and short-stretch compression bandages for treating venous leg ulcers.

METHODS

Cost-effectiveness and cost-utility analyses were performed using patient-level data collected alongside the VenUS I leg ulcer study. The perspective for the economic analysis was that of the UK National Health Service (NHS) and Personal Social Service. The time horizon for the analysis was 1 year after recruitment. Health benefit was measured as differences in ulcer-free days and quality-adjusted life years (QALYs).

RESULTS

The mean healing time for ulcers treated with four-layer bandages was 10.9 (95 per cent confidence interval (c.i.) -6.8 to 29.1) days less than that for ulcers treated with short-stretch bandages. Mean average difference in QALYs between compression systems was -0.02 (95 per cent c.i. -0.08 to 0.04). The four-layer bandage cost a mean of pound 227.32 (95 per cent c.i. pound 16.53 to pound 448 .30) less per patient per year than the short-stretch bandage.

CONCLUSION

On average, four-layer bandaging was associated with greater health benefits and lower costs than short-stretch bandaging.

摘要

背景

本研究调查了四层和短拉伸压缩绷带治疗下肢静脉溃疡的成本效益。

方法

使用在VenUS I下肢溃疡研究中收集的患者层面数据进行成本效益和成本效用分析。经济分析的视角是英国国家医疗服务体系（NHS）和个人社会服务。分析的时间范围是招募后1年。健康效益以无溃疡天数和质量调整生命年（QALYs）的差异来衡量。

结果

用四层绷带治疗的溃疡平均愈合时间比用短拉伸绷带治疗的溃疡少10.9天（95%置信区间（c.i.）-6.8至29.1）。两种压缩系统之间QALYs的平均差异为-0.02（95% c.i. -0.08至0.04）。四层绷带每位患者每年的平均成本比短拉伸绷带少227.32英镑（95% c.i. 16.53英镑至448.30英镑）。