一项关于诊室漂白系统对牙釉质和牙本质完整性影响的体外安全性研究。

A safety study in vitro for the effects of an in-office bleaching system on the integrity of enamel and dentine.

作者信息

Sulieman M, Addy M, Macdonald E, Rees J S

机构信息

Division fo Restorative Dentistry, Department of Oral and Dental Science, University of Bristol Dental School, UK.

出版信息

J Dent. 2004 Sep;32(7):581-90. doi: 10.1016/j.jdent.2004.06.003.

DOI:10.1016/j.jdent.2004.06.003

PMID:15386865

Abstract

OBJECTIVE

The aim of this study was to investigate safety concerns with bleaching procedures by studying the effects of a high concentration hydrogen peroxide (HP) in-surgery bleaching product on enamel and dentine.

METHOD

Flat enamel and dentine samples embedded in epoxy resin were prepared from human third molar teeth. Erosion of enamel: groups of enamel samples were treated with 35% HP then citric acid (CA) or brushing with toothpaste or CA alone and water alone. Enamel Loss was measured using a profilometer. Abrasion/erosion of dentine: groups of dentine specimens were treated as follows: Group 1--brushed with water for 30 min. Group 2--brushed with 35% HP for 30 min. Group 3--power bleached for 30 min and then Group 4--brushed with toothpaste for 1 minute. Group 5--water soaked for 30 min followed by brushing with toothpaste for 1 min. Group 6--orange juice soaked for 30 min followed by brushing with toothpaste for 1 min. Treatment effects were measured using a profilometer. Hardness tests: enamel and dentine specimens were hardness tested using a Wallace indenter prior to and post bleaching. Scanning Electron Microscopy: enamel and dentine specimens were taped and the exposed tissue treated with 35% HP and then studied under scanning electronmicroscopy (SEM).

RESULTS

Enamel erosion: bleaching enamel samples had no measurable effect on enamel. Pre-bleaching had no significant effect on subsequent CA erosion or brushing. Abrasion/erosion of dentine: no significant differences were found between treatments 1-5 with little change from baseline detected. Orange juice (Group 6) produced considerable and significantly more erosion than other treatments. Hardness tests: there were no significant changes in hardness values for enamel and dentine. SEM: there was no evidence of any topographical changes to either enamel or dentine.

CONCLUSION

Using one of the highest concentrations of HP for tooth bleaching procedures and maximum likely peroxide exposure, there was no evidence of deleterious effects on enamel or dentine. It must be assumed that studies which reported adverse effects on enamel and or dentine of bleaches reflect not the bleach itself but the pH of the formulation used.

摘要

目的

本研究旨在通过研究高浓度过氧化氢（HP）手术内漂白产品对牙釉质和牙本质的影响，调查漂白程序的安全性问题。

方法

从人类第三磨牙制备嵌入环氧树脂的扁平牙釉质和牙本质样本。牙釉质侵蚀：将牙釉质样本分组，分别用35% HP处理，然后用柠檬酸（CA）处理，或用牙膏刷牙，或仅用CA处理，或仅用水处理。使用轮廓仪测量牙釉质损失。牙本质磨损/侵蚀：将牙本质标本分组，处理如下：第1组——用水刷牙30分钟。第2组——用35% HP刷牙30分钟。第3组——进行动力漂白30分钟，然后第4组——用牙膏刷牙1分钟。第5组——用水浸泡30分钟，然后用牙膏刷牙1分钟。第6组——用橙汁浸泡30分钟，然后用牙膏刷牙1分钟。使用轮廓仪测量处理效果。硬度测试：在漂白前后，使用华莱士压头对牙釉质和牙本质标本进行硬度测试。扫描电子显微镜：将牙釉质和牙本质标本贴上胶带，用35% HP处理暴露的组织，然后在扫描电子显微镜（SEM）下进行研究。

结果

牙釉质侵蚀：漂白牙釉质样本对牙釉质没有可测量的影响。漂白前对随后的CA侵蚀或刷牙没有显著影响。牙本质磨损/侵蚀：在处理1 - 5组之间未发现显著差异，与基线相比变化很小。橙汁（第6组）产生的侵蚀比其他处理显著得多。硬度测试：牙釉质和牙本质的硬度值没有显著变化。扫描电子显微镜：没有证据表明牙釉质或牙本质有任何表面形貌变化。