Dental Caries Prevention Research Center, Qazvin University of Medical Sciences, Shahid Bahonar Boulevard, Qazvin, Iran.
Department of Operative Dentistry, School of Dentistry, Alborz University of Medical Sciences, Golshahr, Karaj, Iran.
BMC Oral Health. 2024 Apr 12;24(1):445. doi: 10.1186/s12903-024-04195-9.
Considering the extensive use of bleaching agents and the occurrence of side effects such as enamel demineralization, this study aimed to assess the enamel changes of bleached teeth following the experimental application of chitosan-bioactive glass (CH-BG).
In this in vitro study, CH-BG (containing 66% BG) was synthesized and characterized by Fourier-transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD). Thirty sound human premolars were bleached with 40% hydrogen peroxide, and the weight% of calcium and phosphorus elements of the buccal enamel surface was quantified before and after bleaching by scanning electron microscopy/ energy-dispersive X-ray spectroscopy (SEM, EDX). Depending on the surface treatment of the enamel surface, the specimens were divided into three groups (n = 10): control (no treatment), MI Paste (MI), and CH-BG. Then the specimens were stored in artificial saliva for 14 days. The SEM/EDX analyses were performed again on the enamel surface. Data were analyzed by one-way ANOVA and Tukey's test and a p-value of < 0.05 was considered statistically significant.
In all groups, the weight% of calcium and phosphorus elements of enamel decreased after bleaching; this reduction was significant for phosphorus (p < 0.05) and insignificant for calcium (p > 0.05). After 14 days of remineralization, the weight% of both calcium and phosphorus elements was significantly higher compared to their bleached counterparts in both MI and CH-BG groups (p < 0.05). Following the remineralization process, the difference between MI and CH-BG groups was not significant (p > 0.05) but both had a significant difference with the control group in this regard (p < 0.05).
The synthesized CH-BG compound showed an efficacy comparable to that of MI Paste for enamel remineralization of bleached teeth.
考虑到漂白剂的广泛使用以及釉质脱矿等副作用的发生，本研究旨在评估壳聚糖-生物活性玻璃（CH-BG）实验应用后漂白牙齿的釉质变化。
在这项体外研究中，合成并通过傅里叶变换红外光谱（FTIR）和 X 射线衍射（XRD）对壳聚糖-生物活性玻璃（CH-BG）进行了表征。用 40%双氧水对 30 颗健康的人前磨牙进行漂白，并用扫描电子显微镜/能谱仪（SEM、EDX）对颊面釉质表面的钙和磷元素的重量百分比进行定量分析，在漂白前后。根据釉质表面的处理方式，将标本分为三组（n=10）：对照组（无处理）、MI 糊剂（MI）和 CH-BG。然后将标本储存在人工唾液中 14 天。再次对釉质表面进行 SEM/EDX 分析。数据采用单因素方差分析和 Tukey 检验，p 值<0.05 为统计学显著。
所有组中，漂白后釉质中钙和磷元素的重量百分比均降低；磷的降低具有统计学意义（p<0.05），而钙的降低不具有统计学意义（p>0.05）。经过 14 天的再矿化，MI 和 CH-BG 组的钙和磷元素的重量百分比均明显高于相应的漂白组（p<0.05）。再矿化后，MI 和 CH-BG 组之间的差异无统计学意义（p>0.05），但与对照组相比，这两组在这方面均有显著差异（p<0.05）。
合成的 CH-BG 化合物在漂白牙齿的釉质再矿化方面显示出与 MI 糊剂相当的功效。
Zotero 插件
