从圆叶茑萝根中分离并鉴定出五种新的四糖糖苷及其细胞毒性活性。
Isolation and characterization of five new tetrasaccharide glycosides from the roots of Ipomoea stans and their cytotoxic activity.
作者信息
León Ismael, Enríquez Raúl G, Gnecco Dino, Villarreal María L, Cortés Daniel Alonso, Reynolds William F, Yu Margaret
机构信息
Centro de Investigaciones Químicas, Universidad Autónoma del Estado de Morelos, Avenida Universidad 1001, Col. Chamilpa 62210 Cuernavaca, Morelos, México.
出版信息
J Nat Prod. 2004 Sep;67(9):1552-6. doi: 10.1021/np0400454.
PMID:15387658
Abstract
Five new tetrasaccharide glycosides, stansins 1-5, were isolated from the roots of Ipomoea stans, and their structures were elucidated using spectroscopic and chemical methods. Preliminary testing showed the cytotoxicity of 5 toward the OVCAR and UISO-SQC-1 cancer cell lines.
摘要
从茑萝的根中分离出了五种新的四糖糖苷，即茑萝素1 - 5，并通过光谱和化学方法对其结构进行了鉴定。初步测试表明化合物5对OVCAR和UISO - SQC - 1癌细胞系具有细胞毒性。
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