长跑运动员的胆固醇代谢

Cholesterol metabolism in distance runners.

作者信息

Sutherland W H, Nye E R, Macfarlane D J, Williamson S A, Robertson M C

机构信息

Department of Medicine, University of Otago, Dunedin, New Zealand.

出版信息

Clin Physiol. 1992 Jan;12(1):29-37. doi: 10.1111/j.1475-097x.1992.tb00291.x.

DOI:10.1111/j.1475-097x.1992.tb00291.x

PMID:1541082

Abstract

Faecal steroid excretion, including betasitosterol excretion, whole-body cholesterol synthesis, plasma lipids, and lipoprotein concentrations and habitual diet, were determined in 14 male distance runners and 14 sedentary men. The proportion of cholesterol-derived steroids excreted as bile acids, and the quantity of betasitosterol excreted in the faeces were significantly (P less than 0.05) higher in the runners compared with the sedentary men. Faecal betasitosterol excretion and the proportion of cholesterol-derived steroids excreted as bile acids were correlated significantly in the distance runners and the sedentary men (r = 0.774, n = 28, P less than 0.001). These results suggest that greater dietary intake of plant sterols may contribute to the higher proportion of cholesterol-derived steroids excreted as bile acids in distance runners.

摘要

对14名男性长跑运动员和14名久坐不动的男性测定了粪便类固醇排泄（包括β-谷甾醇排泄）、全身胆固醇合成、血浆脂质、脂蛋白浓度以及习惯饮食。与久坐不动的男性相比，长跑运动员中作为胆汁酸排泄的胆固醇衍生类固醇比例以及粪便中排泄的β-谷甾醇量显著更高（P<0.05）。长跑运动员和久坐不动的男性中，粪便β-谷甾醇排泄与作为胆汁酸排泄的胆固醇衍生类固醇比例显著相关（r = 0.774，n = 28，P<0.001）。这些结果表明，植物甾醇的饮食摄入量增加可能有助于长跑运动员中作为胆汁酸排泄的胆固醇衍生类固醇比例更高。