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长跑运动员粪便中胆汁酸的浓度。

Fecal bile acid concentration in distance runners.

作者信息

Sutherland W H, Nye E R, Macfarlane D J, Robertson M C, Williamson S A

机构信息

Department of Medicine, University of Otago, Dunedin, New Zealand.

出版信息

Int J Sports Med. 1991 Dec;12(6):533-6. doi: 10.1055/s-2007-1024729.

DOI:10.1055/s-2007-1024729
PMID:1665841
Abstract

Fecal bile acid concentration, fecal characteristics, bowel habits and habitual food intake were measured in male distance runners (n = 14) and sedentary men (n = 14). Fecal bile acid concentration was significantly (p less than 0.05) lower and stool weight, frequency of defecation and daily intake of fibre, carbohydrate, and protein were significantly (p less than 0.01) higher in the runners. After adjustment for differences in dietary fibre intake, fecal bile acid concentration was no longer significantly different between the distance runners and the sedentary men, but frequency of defecation remained significantly (p less than 0.05) higher in the runners. This study has identified lower fecal bile acid concentration in distance runners, which was probably due mainly to dilution of colon contents by higher consumption of dietary fibre. These findings may be relevant to the reduced incidence of colon cancer in physically active subjects.

摘要

对男性长跑运动员(n = 14)和久坐不动的男性(n = 14)测量了粪便胆汁酸浓度、粪便特征、排便习惯和日常食物摄入量。长跑运动员的粪便胆汁酸浓度显著更低(p < 0.05),而粪便重量、排便频率以及纤维、碳水化合物和蛋白质的每日摄入量显著更高(p < 0.01)。在对膳食纤维摄入量的差异进行调整后,长跑运动员和久坐男性之间的粪便胆汁酸浓度不再有显著差异,但长跑运动员的排便频率仍然显著更高(p < 0.05)。本研究发现长跑运动员的粪便胆汁酸浓度较低,这可能主要是由于膳食纤维摄入量较高导致结肠内容物被稀释。这些发现可能与体力活动者结肠癌发病率降低有关。

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Fecal bile acid concentration in distance runners.长跑运动员粪便中胆汁酸的浓度。
Int J Sports Med. 1991 Dec;12(6):533-6. doi: 10.1055/s-2007-1024729.
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Acute effects of dietary cholic acid and methylazoxymethanol acetate on colon epithelial cell proliferation; metabolism of bile salts and neutral sterols in conventional and germfree SD rats.膳食胆酸和乙酸甲基偶氮甲醇对结肠上皮细胞增殖的急性影响;常规和无菌SD大鼠中胆盐和中性固醇的代谢
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Fecal bile acid excretion in patients with colon cancer, colon polyp and peptic ulcer.结肠癌、结肠息肉和消化性溃疡患者的粪便胆汁酸排泄情况。
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