Weber K E
Department of Ecology, Evolution and Behavior, University of Minnesota, Minneapolis 55455.
Genetics. 1992 Feb;130(2):345-53. doi: 10.1093/genetics/130.2.345.
Two lines of Drosophila melanogaster from the same base population were selected in opposite directions to produce simultaneous antagonistic changes in two very small (less than 0.2 mm) and closely adjacent (less than 0.3 mm) dimensions within the base of the wing. Wing dimensions near the targeted area became differentiated by large positive and negative percentage differences, while only small homogeneous percentage changes occurred in the remainder of the wing. If very small regions of morphology (less than 100 cells across) can respond to selection almost independently, even in small population samples, then the control of developmental detail must involve many genes, and the diversity of possible outcomes in development and adaptation must be large.
从同一基础种群中选取了两系黑腹果蝇，沿相反方向进行选择，以在翅基部两个非常小（小于0.2毫米）且紧密相邻（小于0.3毫米）的维度上同时产生拮抗变化。目标区域附近的翅尺寸通过较大的正负百分比差异而分化，而翅的其余部分仅出现小的均匀百分比变化。如果非常小的形态区域（横向小于100个细胞）即使在小群体样本中也能几乎独立地对选择作出反应，那么发育细节的控制必定涉及许多基因，并且发育和适应中可能结果的多样性必定很大。
