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犬非骨水泥型全髋关节置换模型中两年时骨的重塑与长入

Remodeling and ingrowth of bone at two years in a canine cementless total hip-arthroplasty model.

作者信息

Sumner D R, Turner T M, Urban R M, Galante J O

机构信息

Department of Orthopedic Surgery, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois 60612.

出版信息

J Bone Joint Surg Am. 1992 Feb;74(2):239-50.

PMID:1541618
Abstract

Remodeling and ingrowth of bone in association with the use of uncemented femoral components were examined at two years in a canine total hip-arthroplasty model. Twenty-two dogs received a unilateral uncemented femoral stem that was made of Ti6A14V and was covered with one of three types of titanium porous coating: fiber-metal, beads, or plasma flame-spray. The amount and distribution of ingrowth of bone differed somewhat among the groups at two years, but the patterns of remodeling of bone in the medullary canal and cortex were similar. In general, about 15 to 18 per cent of the cortical bone was lost adjacent to the levels of the stem that were covered with the porous coating. Most of the loss of cortical bone was due to subperiosteal resorption proximally and endosteal resorption at the middle and distal levels of the stem. Increased cortical porosity accounted for only a small fraction of the loss of cortical bone. The amount of medullary bone increased proximally and distally, so that the loss of total bone mass was significantly only at the mid-part of the stem. The amount of loss of cortical bone was similar to that observed in a previous six-month study, suggesting that a steady state was achieved in the present model.

摘要

在犬类全髋关节置换模型中,对使用非骨水泥型股骨假体两年后骨的重塑和长入情况进行了研究。22只犬接受了单侧非骨水泥型股骨柄,该股骨柄由Ti6A14V制成,并覆盖有三种类型的钛多孔涂层之一:纤维金属、珠粒或等离子火焰喷涂。两年时,各组之间骨长入的数量和分布略有不同,但髓腔和皮质骨的重塑模式相似。一般来说,在覆盖有多孔涂层的柄水平附近,约15%至18%的皮质骨丢失。皮质骨的大部分丢失是由于近端的骨膜下吸收以及柄中部和远端的骨内膜吸收。皮质骨孔隙率增加仅占皮质骨丢失的一小部分。近端和远端的髓质骨量增加,因此仅在柄的中部总骨量有显著丢失。皮质骨的丢失量与之前一项为期六个月的研究所观察到的相似,这表明在当前模型中达到了一种稳定状态。

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