Mukarram Ali Baig M, Habibullah C M, Swamy M, Hassan I, Ayesha Q, Devi B G
Department of Gastroenterology, Osmania General Hospital, Hyderabad Andhra, Pradesh, India.
Pediatr Res. 1992 Feb;31(2):143-5. doi: 10.1203/00006450-199202000-00010.
Urea cycle enzymes involved in the detoxification of ammonia were studied in liver tissues of 57 male and 49 female fetuses of different age groups ranging from 13 to 36 wk of gestation. Surgical wedge biopsies of liver from 18 male and 12 female adults were used as controls. Significant enzyme activity was found to be present as early as the 13th wk of gestation. As gestational age advanced, enzyme activity gradually increased, reaching about 90% of the adult activity by the 36th wk of gestation.
对妊娠13至36周不同年龄组的57例男性胎儿和49例女性胎儿的肝脏组织中参与氨解毒的尿素循环酶进行了研究。将18例成年男性和12例成年女性肝脏的手术楔形活检组织用作对照。早在妊娠第13周就发现有显著的酶活性。随着胎龄增加，酶活性逐渐升高，到妊娠第36周时达到成年活性的约90%。
