Alberts M J, Perry A, Dawson D V, Bertels C
Department of Medicine, Duke University Medical Center, Durham, NC 27710.
Stroke. 1992 Mar;23(3):352-6. doi: 10.1161/01.str.23.3.352.
Several emerging stroke therapies require patients to be treated within several hours of symptom onset. Past studies have documented a significant delay between symptom onset and hospital presentation. As part of an experimental treatment study using tissue-type plasminogen activator, we began a multifaceted program of public and professional education to reduce the delay in presentation and referral of acute stroke patients.
The educational efforts focused on improving the recognition of stroke symptoms, the study enrollment criteria, and the need for rapid treatment of stroke patients. This program included 1) interviews on television and radio, 2) newspaper articles, 3) lectures to local and regional primary care and emergency department physicians, 4) mailings to several thousand local physicians, 5) having neurologists on-call for referrals 24 hrs/day, and 6) use of the Duke Life-Flight helicopter.
Since starting our program, 139 of 159 (86%) patients with cerebral infarction presented primarily to our were referred to our facility within 24 hours of symptom onset, compared with 70 of 187 (37%) before our educational efforts (p less than 0.00001). No significant change was seen in patients with intracerebral hemorrhage (23 of 30 +AD77%+BD within 24 hours after program, compared with 25 of 40 +AD63%+BD before educational efforts; p = 0.30).
These findings suggest that educational efforts aimed at the public and health professionals may increase recognition of stroke symptoms and reduce the delay in presentation and referral of stroke patients.
几种新兴的中风治疗方法要求患者在症状出现后的数小时内接受治疗。过去的研究记录了症状出现与入院就诊之间存在显著延迟。作为一项使用组织型纤溶酶原激活剂的实验性治疗研究的一部分,我们启动了一项多方面的公众和专业教育计划,以减少急性中风患者就诊和转诊的延迟。
教育工作重点在于提高对中风症状的认识、研究纳入标准以及对中风患者进行快速治疗的必要性。该计划包括:1)电视和广播访谈;2)报纸文章;3)面向当地及地区基层医疗和急诊科医生的讲座;4)向数千名当地医生邮寄资料;5)安排神经科医生每天24小时待命接受转诊;6)使用杜克生命救援直升机。
自我们的计划启动以来,159例脑梗死患者中有139例(86%)在症状出现后的24小时内主要被转诊至我们的机构,而在我们开展教育工作之前,187例患者中有70例(37%)(p<0.00001)。脑出血患者未见显著变化(计划实施后24小时内30例中有23例,即77%;教育工作前40例中有25例,即63%;p = 0.30)。
这些发现表明,针对公众和卫生专业人员的教育工作可能会提高对中风症状的认识,并减少中风患者就诊和转诊的延迟。