Herse P R
Department of Optometry, University of Auckland, New Zealand.
Invest Ophthalmol Vis Sci. 1992 Mar;33(3):611-7.
The relationships between dioptric blur, pupil size, retinal eccentricity, and retinal sensitivity were investigated in the central 5 degrees of the visual field in 10 normal subjects using the Humphrey Field Analyzer. Pupil size did not influence the foveal sensitivity or retinal profile in the unblurred condition. The slope of the retinal profile was significantly steeper in the 3 mm pupil size condition (-0.62 dB/degree) than when compared to the 8 mm pupil size condition (-0.34 dB/degree), when averaged over all dioptric blur conditions. The depth of focus for the 3 mm pupil size condition (3.86 diopters) was significantly greater than that found for the 8 mm pupil size condition (1.82 D). The retinal threshold doubling eccentricity (E2) was calculated to be similar to that of grating acuity and contrast sensitivity (3.71). The data suggest that while large depth of focus effects in small pupil sizes appear to reduce the need for accurate refractive error corrections in determining perimetric retinal sensitivities, variations in the slope of the retinal profile under conditions of uncontrolled dioptric blur and pupil size may result in the artifactual sensitivity decreases. Therefore, it is recommended that measurement of pupil size and accurate correction of near refractive errors be performed to minimize the possibility of incorrect detection of central visual field defects.
使用汉弗莱视野分析仪，对10名正常受试者视野中心5度范围内的屈光性模糊、瞳孔大小、视网膜偏心度和视网膜敏感度之间的关系进行了研究。在未模糊状态下，瞳孔大小不影响中央凹敏感度或视网膜轮廓。在所有屈光性模糊条件下进行平均时，3毫米瞳孔大小条件下视网膜轮廓的斜率（-0.62 dB/度）明显比8毫米瞳孔大小条件下（-0.34 dB/度）更陡。3毫米瞳孔大小条件下的焦深（3.86屈光度）明显大于8毫米瞳孔大小条件下的焦深（1.82 D）。经计算，视网膜阈值加倍偏心度（E2）与光栅视力和对比敏感度的相似（3.71）。数据表明，虽然小瞳孔大小下较大的焦深效应似乎在确定视野视网膜敏感度时减少了对精确屈光不正矫正的需求，但在屈光性模糊和瞳孔大小未得到控制的情况下，视网膜轮廓斜率的变化可能会导致人为的敏感度降低。因此，建议测量瞳孔大小并准确矫正近屈光不正，以尽量减少错误检测中央视野缺损的可能性。
