de Koning G A, Notowicz A, Stolz E
Hautarzt. 1979 Jan;30(1):27-9.
The case history of a 50-year-old assistant pharmacist, who had been working with 8-methoxypsoralene (8-MOP) without any protection, is discussed. Shortly after this work, he was exposed to sunlight. Within 72 h he developed a typical local reaction with painful erythema and vesiculation on the back of both hands, followed by hyperpigmentation a week later. Light testing on skin dusted with 8-MOP resulted in the same clinical picture. Histopathological examination of a lesion showed the characteristics of a phototoxic dermatitis. Guidelines for the prevention of complications in those who are professionally exposed to 8-MOP are emphasized.
讨论了一名50岁助理药剂师的病例史，该药剂师在未采取任何防护措施的情况下接触了8-甲氧基补骨脂素（8-MOP）。在这项工作后不久，他暴露于阳光下。72小时内，他双手背部出现典型的局部反应，伴有疼痛性红斑和水疱，一周后出现色素沉着。对涂抹8-MOP的皮肤进行光测试产生了相同的临床表现。病变的组织病理学检查显示为光毒性皮炎的特征。强调了预防职业性接触8-MOP者并发症的指南。
