京特·格里施与盘基网柄菌，变形虫运动和多细胞形态发生的微生物模型。

Guenther Gerisch and Dictyostelium, the microbial model for ameboid motility and multicellular morphogenesis.

作者信息

Bozzaro Salvatore, Fisher Paul R, Loomis William, Satir Peter, Segall Jeffrey E

机构信息

Clinical and Biological Sciences, University of Torino, Orbassano 10043, Italy.

出版信息

Trends Cell Biol. 2004 Oct;14(10):585-8. doi: 10.1016/j.tcb.2004.09.006.

DOI:10.1016/j.tcb.2004.09.006

PMID:15450981

Abstract

Beginning in 1960 and continuing to this day, Guenther Gerisch's work on the social ameba Dictyostelium discoideum has helped to make it the model organism of choice for studies of cellular activities that depend upon the actomyosin cytoskeleton. Gerisch has brought insight and quantitative rigor to cell biology by developing novel assays and by applying advanced genetic, biochemical and microscopic techniques to topics as varied as cell-cell adhesion, chemotaxis, motility, endocytosis and cytokinesis.

摘要

从1960年开始一直持续至今，京特·格里施对社会变形虫盘基网柄菌的研究，使其成为研究依赖于肌动球蛋白细胞骨架的细胞活动的首选模式生物。格里施通过开发新的检测方法，并将先进的遗传学、生物化学和显微镜技术应用于细胞间粘附、趋化性、运动性、内吞作用和胞质分裂等各种主题，为细胞生物学带来了深刻见解和定量严谨性。