Devreotes P
Department of Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD 21205.
Science. 1989 Sep 8;245(4922):1054-8. doi: 10.1126/science.2672337.
The cellular slime mold Dictyostelium discoideum undergoes a transition from single-celled amoebae to a multicellular organism as a natural part of its life cycle. A method of cell-cell signaling that controls chemotaxis, morphogenesis, and gene expression has developed in this organism, and a detailed understanding of this signaling system provides clues to mechanisms of intercellular communication in the development of metazoans.
细胞黏菌盘基网柄菌在其生命周期的自然过程中会经历从单细胞变形虫到多细胞生物体的转变。在这种生物体中已经形成了一种控制趋化性、形态发生和基因表达的细胞间信号传导方法，对这一信号系统的详细了解为后生动物发育过程中的细胞间通讯机制提供了线索。
