Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.
Microbiology (Reading). 2021 Mar;167(3). doi: 10.1099/mic.0.001040. Epub 2021 Mar 1.
The social amoeba is a versatile organism that is unusual in alternating between single-celled and multi-celled forms. It possesses highly-developed systems for cell motility and chemotaxis, phagocytosis, and developmental pattern formation. As a soil amoeba growing on microorganisms, it is exposed to many potential pathogens; it thus provides fruitful ways of investigating host-pathogen interactions and is emerging as an influential model for biomedical research.
黏菌是一种多功能生物体,其独特之处在于能够在单细胞和多细胞形态之间交替。它具有高度发达的细胞运动和趋化性、吞噬作用和发育模式形成系统。作为一种在微生物上生长的土壤黏菌,它会接触到许多潜在的病原体;因此,它为研究宿主-病原体相互作用提供了富有成效的途径,并且正在成为生物医学研究的有影响力的模型。