Pérez Montiel Delia, Puebla Mora Ana Graciela, Cantú de León David
Departamento de patología quirúgica, Instituto Nacional de Cancerología, México, DF.
Ginecol Obstet Mex. 2004 May;72:215-8.
Malignant vulvar tumors account for less than 1% of the malignant lesions in women and between 3 to 5% of the malignant tumors from female genital tract. The most common malignant neoplasia is squamous cell carcinoma followed by melanoma and in last place sarcomas and metastasis.
To report the incidence and experience at the Instituto Nacional de Cancerologia of Mexico.
Vulvar metastasis were recorded from the files of pathology department of the Instituto Nacional de Cancerologia diagnosed from 1984 to 2002. Clinical and histological characteristics from these cases were evaluated as well as clinical behavior.
Eight cases of vulvar metastasis were found from a total of 436 malignant vulvar neoplasias (1.8%). Primary tumor in six cases was located in genital area; in the other two the primary tumor was located in breast and bladder. Labium majus was the most frequent site of metastasis. All the patients died with disease progression in a period of one month to one year after the diagnosis of vulvar metastasis.
Vulvar metastasis is a rare phenomenon; these lesions are in relation to advanced clinical stage and a poor prognosis.
恶性外阴肿瘤占女性恶性病变的比例不到1%，占女性生殖道恶性肿瘤的3%至5%。最常见的恶性肿瘤是鳞状细胞癌，其次是黑色素瘤，肉瘤和转移瘤位居最后。
报告墨西哥国家癌症研究所的发病率及经验。
从墨西哥国家癌症研究所病理科1984年至2002年诊断的病例档案中记录外阴转移情况。对这些病例的临床和组织学特征以及临床行为进行评估。
在436例恶性外阴肿瘤中发现8例外阴转移（1.8%）。6例原发肿瘤位于生殖区域；另外2例原发肿瘤位于乳腺和膀胱。大阴唇是最常见的转移部位。所有患者在诊断外阴转移后的1个月至1年内均因疾病进展死亡。
外阴转移是一种罕见现象；这些病变与临床晚期和预后不良有关。
