Ishizaki Tatsuro, Kai Ichiro, Kobayashi Yasuki, Matsuyama Yutaka, Imanaka Yuichi
Department of Healthcare Economics and Quality Management, School of Public Health, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Aging Clin Exp Res. 2004 Jun;16(3):233-9. doi: 10.1007/BF03327389.
Using longitudinal data analyses, we examined the effects of aging on functional decline, based on activities of daily living (ADL) and instrumental activities of daily living (IADL) during a 5-year follow-up among older people living in a community in Japan.
The baseline survey in July 1988 involved all elderly residents aged 60 or older in Saku City, Nagano, Japan (N=13418). All survivors of this cohort were asked to participate in follow-up surveys conducted in 1989, 1990, 1991, 1992 and 1993. Five items of ADL and five of IADL were measured on each survey. A generalized estimating equations (GEE) analysis was used to examine the effects of aging on the increase of the proportion of subjects with functional dependence.
These results indicated that the proportion of subjects who were dependent in ADL increased during the 5-year period by 2.2 times (p<0.001) and the proportion of those who were dependent in either ADL or IADL increased during the same period by 1.8 times (p<0.001). Gender did not appear to be significantly associated with functional decline.
The GEE analysis in this study identified the statistically significant effect of aging on the increase of the proportion of subjects with functional dependence based on ADL and IADL.
我们运用纵向数据分析，基于日本某社区老年人5年随访期间的日常生活活动（ADL）和工具性日常生活活动（IADL），研究衰老对功能衰退的影响。
1988年7月的基线调查涵盖了日本长野县佐久市所有60岁及以上的老年居民（N = 13418）。该队列的所有幸存者被要求参与1989年、1990年、1991年、1992年和1993年进行的随访调查。每次调查均测量5项ADL和5项IADL。采用广义估计方程（GEE）分析来研究衰老对功能依赖受试者比例增加的影响。
这些结果表明，在这5年期间，ADL依赖受试者的比例增加了2.2倍（p < 0.001），ADL或IADL依赖受试者的比例在同一时期增加了1.8倍（p < 0.001）。性别似乎与功能衰退无显著关联。
本研究中的GEE分析确定了衰老对基于ADL和IADL的功能依赖受试者比例增加具有统计学显著影响。
