King C A
Department of Biology, University College, Gower Street, London WCIE, 6BT, UK.
Parasitol Today. 1988 Nov;4(11):315-9. doi: 10.1016/0169-4758(88)90113-5.
Parasitic protozoa need to be capable of movement. This is particularly important for their ability to locate and invade target cells or the organs of their hosts, and could therefore represent a novel target for chemotherapy or immune-mediated attack. Unlike the crawling movement of amoebae and vertebrate fibroblasts, sporozoon protozoa are characterized by a 'gliding movement' in which no obvious changes occur in cell shape. Here Conrad King discusses cellular motility particularly in sporozoites of Eimeria and Plasmodium, discussing current ideas about the possible motor mechanisms involved.
寄生原生动物需要具备运动能力。这对于它们定位和侵入靶细胞或宿主器官的能力尤为重要,因此可能成为化疗或免疫介导攻击的新靶点。与变形虫和脊椎动物成纤维细胞的爬行运动不同,孢子虫原生动物的特征是“滑行运动”,在此过程中细胞形状没有明显变化。康拉德·金在此讨论细胞运动性,特别是艾美球虫和疟原虫的子孢子的运动性,并探讨了有关可能涉及的运动机制的当前观点。