利用重组DNA技术诊断恰加斯病。
Diagnosis of Chagas disease using recombinant DNA technology.
作者信息
Frasch A C, Reyes M B
机构信息
Instituto de Investigaciones Bioquímicas Fundación Campomar, Antonio Machado 151, 1405 Buenos Aires, Argentina.
出版信息
Parasitol Today. 1990 Apr;6(4):137-9. doi: 10.1016/0169-4758(90)90234-u.
PMID:15463319
Abstract
In this article, Alberto Frasch and Maria Reyes discuss the development of new tools for the serodiagnosis of Chagas disease (caused by Trypanosoma cruzi) and describe recombinant antigens that have proved to be of great diagnostic potential in distinguishing different stages of the disease. The work is important because different treatment strategies are needed for acute and chronic infection.
摘要
在本文中，阿尔贝托·弗拉施和玛丽亚·雷耶斯讨论了用于恰加斯病（由克氏锥虫引起）血清诊断的新工具的开发，并描述了已被证明在区分该疾病不同阶段具有巨大诊断潜力的重组抗原。这项工作很重要，因为急性和慢性感染需要不同的治疗策略。
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