过氧化物酶体增殖物激活受体γ：其在代谢综合征中的作用
Peroxisome proliferator-activated receptor gamma: its role in metabolic syndrome.
作者信息
Pakala Rajbabu, Kuchulakanti Pramod, Rha Seung-Woon, Cheneau Edouard, Baffour Richard, Waksman Ron
机构信息
Cardiovascular Research Institute, Washington Hospital Center, 110 Irving Street NW, Suite 4B-1, Washington, DC 20010, USA.
出版信息
Cardiovasc Radiat Med. 2004 Apr-Jun;5(2):97-103. doi: 10.1016/j.carrad.2004.03.006.
PMID:15464947
Abstract
Here we review PPARgamma function in relation to human adipogenesis, insulin sensitization, lipid metabolism, blood pressure regulation and prothrombotic state to perhaps provide justification for this nuclear receptor remaining a key therapeutic target for the continuing development of agents to treat human metabolic syndrome.
摘要
在此，我们回顾了过氧化物酶体增殖物激活受体γ（PPARγ）在人类脂肪生成、胰岛素敏感性、脂质代谢、血压调节和血栓前状态方面的功能，以期为该核受体仍是治疗人类代谢综合征药物持续研发的关键治疗靶点提供依据。
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