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采用膨体聚四氟乙烯(PTFE)置入改良远端脾肾分流术后的长期结果。

Long-term results after modified distal splenorenal shunt with expanded PTFE interposition.

作者信息

Nagasue N, Ogawa Y, Yukaya H, Kohno H, Chang Y C, Hayashi T, Yamanoi A, Nakamura T

机构信息

Second Department of Surgery, Shimane Medical University, Izumo, Japan.

出版信息

Zentralbl Chir. 1992;117(1):24-9.

PMID:1546495
Abstract

Forty consecutive patients with esophagogastric varices underwent a modified distal splenorenal shunt with expanded polytetrafluoroethylene (PTFE) interposition and were followed up for 12 to 66 months (mean 44.7). The operations were urgent in 9, elective in 14, and prophylactic in 17 patients. There were 24 males and 16 females. Age ranged from 32 to 76 years with an average of 53.8. The causes of portal hypertension were liver cirrhosis in 32, chronic hepatitis in 4, idiopathic portal hypertension in 3, and primary biliary cirrhosis in 1. Twenty-six patients were in Child's class A, 6 in class B, and 8 in class C. The operative death rate within 1 month was 2.5% and the overall in-hospital mortality rate was 5%. The shunt patency rate was 97.2% at early and 100% at late examinations. Only one patient (2.5%) had upper gastrointestinal bleeding. Hepatic encephalopathy was seen in 8 (20.5%) of 39 surviving patients. Six patients died of liver failure and another six died from various causes during the follow-up period. Twenty-six patients (65%) are alive at present. The 1-, 3-, and 5-year cumulative survival rates were 87.4%, 73.3% and 48.8%, respectively. The current modified shunt can be carried out more safely and easily and yield a similar result to that with the original Warren shunt. In order to avoid hepatic encephalopathy and liver failure, however, it is not wise to persist in this procedure.

摘要

40例连续性食管胃静脉曲张患者接受了改良的远端脾肾分流术,术中使用了膨体聚四氟乙烯(PTFE)进行搭桥,并随访了12至66个月(平均44.7个月)。其中9例为急诊手术,14例为择期手术,17例为预防性手术。患者中男性24例,女性16例。年龄范围为32至76岁,平均53.8岁。门静脉高压的病因包括肝硬化32例、慢性肝炎4例、特发性门静脉高压3例、原发性胆汁性肝硬化1例。Child分级A级26例,B级6例,C级8例。术后1个月内手术死亡率为2.5%,总体住院死亡率为5%。早期分流通畅率为97.2%,后期检查时为100%。仅1例患者(2.5%)发生上消化道出血。39例存活患者中有8例(20.5%)出现肝性脑病。随访期间,6例患者死于肝功能衰竭,另6例死于各种原因。目前有26例患者(65%)存活。1年、3年和5年累积生存率分别为87.4%、73.3%和48.8%。目前的改良分流术实施起来更安全、简便,效果与原Warren分流术相似。然而,为避免肝性脑病和肝功能衰竭,坚持该手术并不明智。

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