Nagasue N, Ogawa Y, Yukaya H, Sasaki Y, Tamada R, Chang Y, Nakamura T
Department of Surgery, Hiroshima Red Cross Hospital.
Zentralbl Chir. 1988;113(20):1329-37.
During recent 17 years, prophylactic distal splenorenal shunt was carried out on 29 patients. Patients were composed of 18 males and 11 females. Age ranged from 34 to 66 years with an average of 52.4. All patients had risky esophagogastric varices; varices larger than 5 mm in diameter and or varices with red color signs such as cherry red spots endoscopically. Underlying liver disease were cirrhosis of the liver in 27, chronic hepatitis in one, and idiopathic portal hypertension in one. Twenty-three patients were in Child's class A and six were in class B. Thirteen patients underwent the original Warren shunt but the remaining 16 had modified distal splenorenal shunts with expanded polytetrafluoroethylene interposition. Portal-azygos disconnection was routinely performed. One patients (3.4%) died of hepatic failure on the 6th postoperative day. Four patients (14.3%) developed hepatic encephalopathy of mild to moderate degree but no patients have suffered from variceal bleeding until now. The 5-, 10-, and 15-year survival rates were all 85.5 per cent. It is concluded that distal splenorenal shunt is a safe and reliable method to prevent variceal bleeding in a selected group of patients.
在最近17年里,对29例患者实施了预防性远端脾肾分流术。患者中男性18例,女性11例。年龄在34岁至66岁之间,平均年龄为52.4岁。所有患者均有高危食管胃静脉曲张;内镜下可见直径大于5mm的静脉曲张和/或有红色征像(如樱桃红点)的静脉曲张。基础肝病中,27例为肝硬化,1例为慢性肝炎,1例为特发性门静脉高压。23例患者为Child A级,6例为B级。13例患者接受了最初的Warren分流术,但其余16例接受了带膨体聚四氟乙烯置入的改良远端脾肾分流术。常规进行门奇静脉断流术。1例患者(3.4%)术后第6天死于肝衰竭。4例患者(14.3%)发生轻至中度肝性脑病,但至今无患者发生静脉曲张出血。5年、10年和15年生存率均为85.5%。结论是,远端脾肾分流术是预防特定患者群体静脉曲张出血的一种安全可靠的方法。