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SIFT:一种使用电子射野影像装置来验证患者治疗期间所给予的调强放疗注量的方法。

SIFT: a method to verify the IMRT fluence delivered during patient treatment using an electronic portal imaging device.

作者信息

Vieira Sandra C, Dirkx Maarten L P, Heijmen Ben J M, de Boer Hans C J

机构信息

Department of Radiation Oncology, Division of Clinical Physics, Erasmus MC-Daniel den Hoed Cancer Center, Groene Hilledijk 301, 3075 EA Rotterdam, The Netherlands.

出版信息

Int J Radiat Oncol Biol Phys. 2004 Nov 1;60(3):981-93. doi: 10.1016/j.ijrobp.2004.06.025.

Abstract

PURPOSE

Radiotherapy patients are increasingly treated with intensity-modulated radiotherapy (IMRT) and high tumor doses. As part of our quality control program to ensure accurate dose delivery, a new method was investigated that enables the verification of the IMRT fluence delivered during patient treatment using an electronic portal imaging device (EPID), irrespective of changes in patient geometry.

METHODS AND MATERIALS

Each IMRT treatment field is split into a static field and a modulated field, which are delivered in sequence. Images are acquired for both fields using an EPID. The portal dose image obtained for the static field is used to determine changes in patient geometry between the planning CT scan and the time of treatment delivery. With knowledge of these changes, the delivered IMRT fluence can be verified using the portal dose image of the modulated field. This method, called split IMRT field technique (SIFT), was validated first for several phantom geometries, followed by clinical implementation for a number of patients treated with IMRT.

RESULTS

The split IMRT field technique allows for an accurate verification of the delivered IMRT fluence (generally within 1% [standard deviation]), even if large interfraction changes in patient geometry occur. For interfraction radiological path length changes of 10 cm, deliberately introduced errors in the delivered fluence could still be detected to within 1% accuracy. Application of SIFT requires only a minor increase in treatment time relative to the standard IMRT delivery.

CONCLUSIONS

A new technique to verify the delivered IMRT fluence from EPID images, which is independent of changes in the patient geometry, has been developed. SIFT has been clinically implemented for daily verification of IMRT treatment delivery.

摘要

目的

放射治疗患者越来越多地接受调强放射治疗(IMRT)和高肿瘤剂量治疗。作为我们确保准确剂量输送的质量控制计划的一部分,研究了一种新方法,该方法能够使用电子门静脉成像设备(EPID)验证患者治疗期间所输送的IMRT注量,而不受患者几何形状变化的影响。

方法和材料

每个IMRT治疗野被分为一个静态野和一个调变野,按顺序输送。使用EPID采集两个野的图像。为静态野获得的门静脉剂量图像用于确定计划CT扫描与治疗输送时间之间患者几何形状的变化。了解这些变化后,可使用调变野的门静脉剂量图像验证所输送的IMRT注量。这种方法称为分割IMRT野技术(SIFT),首先针对几种体模几何形状进行了验证,随后对一些接受IMRT治疗的患者进行了临床应用。

结果

分割IMRT野技术能够准确验证所输送的IMRT注量(一般在1%[标准差]以内),即使患者几何形状在分次治疗间发生较大变化。对于故意引入的10 cm分次间放射学路径长度变化,所输送注量中的误差仍能以1%的精度检测到。相对于标准IMRT输送,SIFT的应用仅使治疗时间略有增加。

结论

已开发出一种从EPID图像验证所输送的IMRT注量的新技术,该技术与患者几何形状的变化无关。SIFT已在临床上用于IMRT治疗输送的日常验证。

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