Vieira Sandra C, Bolt René A, Dirkx Maarten L P, Visser Andries G, Heijmen Ben J M
Department of Radiation Oncology, Erasmus MC/Daniel den Hoed Cancer Center, Rotterdam, The Netherlands.
Radiother Oncol. 2006 Jul;80(1):86-92. doi: 10.1016/j.radonc.2006.06.010. Epub 2006 Jul 18.
Intensity modulated radiotherapy (IMRT) requires dedicated quality assurance (QA). Recently, we have published a method for fast (1-2 min) and accurate linac quality control for dynamic multileaf collimation, using a portal imaging device. This method is in routine use for daily leaf motion verification. The purpose of the present study was to develop an equivalent procedure for QA of IMRT with segmented (static) multileaf collimation (SMLC).
The QA procedure is based on measurements performed during 3- to 8-month periods at Elekta, Siemens and Varian accelerators. On each measurement day, images were acquired for a field consisting of five 3 x 22 cm(2) segments. These 10 monitor unit (MU) segments were delivered in SMLC mode, moving the leaves from left to right. Deviations of realized leaf gap widths from the prescribed width were analysed to study the leaf positioning accuracy. To assess hysteresis in leaf positioning, the sequential delivery of the SMLC segments was also inverted. A static 20 x 20 cm(2) field was delivered with exposures between 1 and 50 MU to study the beam output and beam profile at low exposures. Comparisons with an ionisation chamber were made to verify the EPID dose measurements at low MU. Dedicated software was developed to improve the signal-to-noise ratio and to correct for image distortion.
The observed long-term leaf gap reproducibility (1 standard deviation) was 0.1 mm for the Varian, and 0.2 mm for the Siemens and the Elekta accelerators. In all cases the hysteresis was negligible. Down to the lowest MU, beam output measurements performed with the EPID agreed within 1+/-1% (1SD) with ionisation chamber measurements. These findings led to a fast (3-4 min) procedure for accurate, daily linac quality control for SMLC.
调强放射治疗(IMRT)需要专门的质量保证(QA)。最近,我们发表了一种使用门静脉成像设备对动态多叶准直进行快速(1 - 2分钟)且准确的直线加速器质量控制方法。该方法日常用于叶片运动的验证。本研究的目的是开发一种适用于分段(静态)多叶准直(SMLC)的IMRT质量保证等效程序。
质量保证程序基于在Elekta、西门子和瓦里安加速器上进行的3至8个月期间的测量。在每个测量日,获取由五个3×22 cm²段组成的射野图像。这10个监测单位(MU)段以SMLC模式递送,叶片从左向右移动。分析实际叶片间隙宽度与规定宽度的偏差,以研究叶片定位精度。为评估叶片定位中的滞后现象,SMLC段的顺序递送也进行了反转。以1至50 MU的照射量递送一个静态20×20 cm²射野,以研究低照射量下的射束输出和射束轮廓。与电离室进行比较,以验证低MU时的电子射野影像装置(EPID)剂量测量。开发了专用软件以提高信噪比并校正图像失真。
对于瓦里安加速器,观察到的长期叶片间隙再现性(1个标准差)为0.1 mm,对于西门子和Elekta加速器为0.2 mm。在所有情况下,滞后现象均可忽略不计。直至最低MU,使用EPID进行的射束输出测量与电离室测量结果在1±1%(1个标准差)范围内一致。这些结果促成了一种快速(3 - 4分钟)的程序,用于SMLC的准确日常直线加速器质量控制。