Thordstein M, Flisberg A, Löfgren N, Bågenholm R, Lindecrantz K, Wallin B G, Kjellmer I
Institute of Clinical Neuroscience, Unit of Clinical Neurophysiology, Bla straket 7, Sahlgrenska University Hospital, 413 45 Göteborg, Sweden.
Clin Neurophysiol. 2004 Nov;115(11):2461-6. doi: 10.1016/j.clinph.2004.05.019.
To investigate whether the periodic EEG patterns seen in healthy and sick full term neonates (trace alternant and burst suppression, respectively) have different frequency characteristics.
Burst episodes were selected from the EEGs of 9 healthy and 9 post-asphyctic full-term neonates and subjected to power spectrum analysis. Powers in two bands were estimated; 0-4 and 4-30 Hz, designated low- and high-frequency activity, respectively (LFA, HFA). The spectral edge frequency (SEF) was also assessed.
In bursts, the LFA power was lower in periods of burst suppression as compared to those of trace alternant. The parameter that best discriminated between the groups was the relative amount of low- and high-frequency activity. The SEF parameter had a low sensitivity to the group differences. In healthy neonates, the LFA power was higher over the posterior right as compared to the posterior left region.
Spectral power of low frequencies differs significantly between the burst episodes of healthy and sick neonates.
These results can be used when monitoring cerebral function in neonates.
研究健康足月儿和患病足月儿脑电图中出现的周期性模式（分别为交替性图形和爆发抑制）是否具有不同的频率特征。
从9名健康足月儿和9名窒息后足月儿的脑电图中选取爆发期进行功率谱分析。估计两个频段的功率；0 - 4Hz和4 - 30Hz，分别称为低频活动（LFA）和高频活动（HFA）。还评估了频谱边缘频率（SEF）。
在爆发期，爆发抑制期的低频活动功率低于交替性图形期。最能区分两组的参数是低频和高频活动的相对量。SEF参数对组间差异的敏感性较低。在健康足月儿中，右侧后部的低频活动功率高于左侧后部区域。
健康和患病足月儿爆发期的低频频谱功率存在显著差异。
这些结果可用于新生儿脑功能监测。
