• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Opposite effects of interleukin 10 common gene polymorphisms in cardiovascular diseases and in successful ageing: genetic background of male centenarians is protective against coronary heart disease.白细胞介素10常见基因多态性在心血管疾病和成功衰老中的相反作用：男性百岁老人的遗传背景对冠心病具有保护作用。
J Med Genet. 2004 Oct;41(10):790-4. doi: 10.1136/jmg.2004.019885.
2
Inflammation, longevity, and cardiovascular diseases: role of polymorphisms of TLR4.炎症、长寿与心血管疾病：Toll样受体4多态性的作用
Ann N Y Acad Sci. 2006 May;1067:282-7. doi: 10.1196/annals.1354.037.
3
Role of proinflammatory alleles in longevity and atherosclerosis: results of studies performed on -1562C/T MMP-9 in centenarians and myocardial infarction patients from Sicily.促炎等位基因在长寿和动脉粥样硬化中的作用：对西西里岛百岁老人和心肌梗死患者的-1562C/T基质金属蛋白酶-9进行研究的结果
Ann N Y Acad Sci. 2006 Nov;1089:496-501. doi: 10.1196/annals.1386.048.
4
The G/C915 polymorphism of transforming growth factor beta1 is associated with human longevity: a study in Italian centenarians.转化生长因子β1的G/C915多态性与人类长寿相关：一项对意大利百岁老人的研究。
Aging Cell. 2004 Dec;3(6):443-8. doi: 10.1111/j.1474-9728.2004.00129.x.
5
Alpha1-antitrypsin heterozygosity plays a positive role in attainment of longevity.α1-抗胰蛋白酶杂合性在长寿的实现中发挥着积极作用。
Biogerontology. 2007 Apr;8(2):139-45. doi: 10.1007/s10522-006-9041-y. Epub 2006 Sep 20.
6
Inflammatory cytokine gene variants in coronary artery disease patients in Greece.希腊冠心病患者炎症细胞因子基因变异
Coron Artery Dis. 2008 Dec;19(8):575-82. doi: 10.1097/MCA.0b013e32831286e8.
7
14th International HLA and Immunogenetics Workshop: report on the immunogenetics of aging.第十四届国际人类白细胞抗原与免疫遗传学研讨会：衰老免疫遗传学报告
Tissue Antigens. 2007 Apr;69 Suppl 1:304-10. doi: 10.1111/j.1399-0039.2006.00783.x.
8
Role of polymorphisms of CC-chemokine receptor-5 gene in acute myocardial infarction and biological implications for longevity.C-C趋化因子受体5基因多态性在急性心肌梗死中的作用及对长寿的生物学意义。
Haematologica. 2008 Apr;93(4):637-8. doi: 10.3324/haematol.12239.
9
Genetics and the pathobiology of ageing.遗传学与衰老的病理生物学
Philos Trans R Soc Lond B Biol Sci. 1997 Dec 29;352(1363):1773-80. doi: 10.1098/rstb.1997.0161.
10
Additive effects of the chemokine receptor 2, vitamin D receptor, interleukin-6 polymorphisms and cardiovascular risk factors on the prevalence of myocardial infarction in patients below 65 years.趋化因子受体2、维生素D受体、白细胞介素-6基因多态性与心血管危险因素对65岁以下患者心肌梗死患病率的叠加效应。
Int J Cardiol. 2005 Oct 20;105(1):90-5. doi: 10.1016/j.ijcard.2005.03.004.

引用本文的文献

1
Association of IL-10, IL-6, and TNF-α polymorphisms with acute coronary syndrome risk: a systematic review, meta-analysis, and trial sequential analysis.白细胞介素-10、白细胞介素-6和肿瘤坏死因子-α基因多态性与急性冠状动脉综合征风险的关联：一项系统评价、荟萃分析和试验序贯分析
BMC Med Genomics. 2025 Aug 23;18(1):136. doi: 10.1186/s12920-025-02167-8.
2
The aging immune system and all-cause mortality in older americans: differences across sex and race/ethnicity.美国老年人的衰老免疫系统与全因死亡率：性别和种族/族裔差异
Immun Ageing. 2025 Jun 21;22(1):25. doi: 10.1186/s12979-025-00521-z.
3
IL10 promoter variants are associated with gene expression but they are not markers of susceptibility to acute coronary syndrome.白细胞介素 10 启动子变异与基因表达相关，但它们不是急性冠状动脉综合征易感性的标志物。
Sci Rep. 2024 Jun 8;14(1):13196. doi: 10.1038/s41598-024-64097-2.
4
Polymorphisms of Pro-Inflammatory IL-6 and IL-1β Cytokines in Ascending Aortic Aneurysms as Genetic Modifiers and Predictive and Prognostic Biomarkers.炎症细胞因子白细胞介素-6 和白细胞介素-1β 基因多态性与升主动脉瘤的相关性研究：作为遗传修饰因子、预测和预后生物标志物。
Biomolecules. 2021 Jun 25;11(7):943. doi: 10.3390/biom11070943.
5
SARS CoV2 infection _The longevity study perspectives.严重急性呼吸综合征冠状病毒2感染_长寿研究视角
Ageing Res Rev. 2021 May;67:101299. doi: 10.1016/j.arr.2021.101299. Epub 2021 Feb 16.
6
Association between interleukin-10 polymorphisms and CD4CD25FOXP3 T cells in asthmatic children.哮喘患儿白细胞介素-10 多态性与 CD4CD25FOXP3 T 细胞的关系。
J Pediatr (Rio J). 2021 Sep-Oct;97(5):546-551. doi: 10.1016/j.jped.2020.11.008. Epub 2021 Jan 2.
7
IL-10-producing Tfh cells accumulate with age and link inflammation with age-related immune suppression.产生白细胞介素-10的滤泡辅助性T细胞随年龄增长而积累，并将炎症与年龄相关的免疫抑制联系起来。
Sci Adv. 2020 Jul 29;6(31):eabb0806. doi: 10.1126/sciadv.abb0806. eCollection 2020 Jul.
8
Inflammation in Post-Traumatic Stress Disorder (PTSD): A Review of Potential Correlates of PTSD with a Neurological Perspective.创伤后应激障碍（PTSD）中的炎症：从神经学角度对PTSD潜在相关因素的综述
Antioxidants (Basel). 2020 Jan 26;9(2):107. doi: 10.3390/antiox9020107.
9
Lack of Association between Cytokine Genetic Polymorphisms in Takayasu's Arteritis in Mexican Patients.墨西哥患者的 Takayasu 动脉炎中细胞因子遗传多态性缺乏关联。
Int J Environ Res Public Health. 2019 Dec 3;16(23):4863. doi: 10.3390/ijerph16234863.
10
Association of IL-10-1082A/G polymorphism with cardiovascular disease risk: Evidence from a case-control study to an updated meta-analysis.白细胞介素-10-1082A/G 多态性与心血管疾病风险的关联：病例对照研究到更新的荟萃分析证据。
Mol Genet Genomic Med. 2019 Nov;7(11):e888. doi: 10.1002/mgg3.888. Epub 2019 Sep 30.

Opposite effects of interleukin 10 common gene polymorphisms in cardiovascular diseases and in successful ageing: genetic background of male centenarians is protective against coronary heart disease.

作者信息

Lio D, Candore G, Crivello A, Scola L, Colonna-Romano G, Cavallone L, Hoffmann E, Caruso M, Licastro F, Caldarera C M, Branzi A, Franceschi C, Caruso C

出版信息

J Med Genet. 2004 Oct;41(10):790-4. doi: 10.1136/jmg.2004.019885.

DOI:10.1136/jmg.2004.019885
PMID:15466015
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1735604/
Abstract
摘要