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门诊腹股沟疝修补术后持续局部麻醉药输注用于疼痛管理

Continuous local anesthetic infusion for pain management after outpatient inguinal herniorrhaphy.

作者信息

Schurr Michael J, Gordon Debra B, Pellino Teresa A, Scanlon Trisha A

机构信息

Department of Surgery, University of Winsconsin Hospital, Madison, 53792, USA.

出版信息

Surgery. 2004 Oct;136(4):761-9. doi: 10.1016/j.surg.2004.06.016.

Abstract

BACKGROUND

The purpose of the present study is to compare postoperative pain and functional outcomes in patients undergoing inguinal herniorrhaphy who receive a continuous wound infusion of bupivacaine to those who receive an infusion of saline.

METHODS

A prospective, randomized, blinded, placebo-controlled trial was conducted in adults undergoing outpatient inguinal herniorrhaphy. Patients received saline or bupivacaine through a disposable infusion pump for 60 hours postoperatively. Pain outcomes were assessed, as were functional outcomes (activity, return of bowel function) and side effects.

RESULTS

On postoperative day 1, patients who received bupivacaine had lower ratings for worst pain than patients who received saline, (5.0 +/- 2.3 vs 6.7 +/- 2.2, P=.002). On day 1, least pain ratings were also lower, and patients ambulated more frequently than those who received placebo. There were no differences between groups from postoperative days 2 to 5. There were no differences between groups in the amount of hydrocodone consumption.

CONCLUSIONS

Continuous infusion of local anesthetic after inguinal herniorrhaphy provides modest improvements in pain scores and functional outcomes when compared with placebo. However, these effects are limited to the first postoperative day only. The additional costs associated with this intervention may limit its widespread use in clinical practice.

摘要

背景

本研究的目的是比较接受布比卡因持续伤口灌注的腹股沟疝修补术患者与接受生理盐水灌注的患者的术后疼痛和功能结局。

方法

对接受门诊腹股沟疝修补术的成年人进行了一项前瞻性、随机、双盲、安慰剂对照试验。患者术后通过一次性输液泵接受生理盐水或布比卡因治疗60小时。评估疼痛结局、功能结局(活动、肠功能恢复)和副作用。

结果

术后第1天,接受布比卡因的患者的最严重疼痛评分低于接受生理盐水的患者(5.0±2.3对6.7±2.2,P = .002)。在第1天,最低疼痛评分也较低,且患者比接受安慰剂的患者更频繁地走动。术后第2至5天两组之间无差异。两组之间氢可酮的消耗量无差异。

结论

与安慰剂相比,腹股沟疝修补术后持续输注局部麻醉剂可使疼痛评分和功能结局有适度改善。然而,这些效果仅局限于术后第一天。与该干预措施相关的额外费用可能会限制其在临床实践中的广泛应用。

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