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[肌营养不良患者干涉图样分析]

[Analysis of the interference pattern in patients with muscular dystrophy].

作者信息

Escobar-Cedillo R E, Miranda A, Lona S, Castillo M

机构信息

Servicio de Electrodiagnóstico, División de Investigación, Centro Nacional de Rehabilitación, Secretaría de Salud, Mexico DF, Mexico.

出版信息

Rev Neurol. 2004;39(6):517-20.

PMID:15467987
Abstract

INTRODUCTION

The conventional electromyography contribute to differentiation of myopatic and neuropatic patterns in neuromuscular disorders, however, the classical patterns related to myopatic changes can result in neurogenic components, this confusion could be due to denervation and reinervation changes involved at the different stages of those diseases.

OBJECTIVE

Demonstrate the importance of quantitative electromyographic techniques, as the interference pattern analysis (IPA), for a better differentiation of muscular dystrophies.

PATIENTS AND METHODS

IPA was done in 95 patients with 3 different muscular dystrophies: 52 Duchenne muscular dystrophy (DMD), 33 limb girdle muscular dystrophy (LGMD) and 10 myotonic muscular dystrophy (MD) individuals and in a control group of 25 individuals. The left braquial biceps and right anterior tibial muscles were evaluated; the variables analyzed were turns/seconds (t/s), amplitude/turns (a/t), ratio turns/amplitude mean and root squared mean (RSM).

RESULTS

We found statistical significant differences in all variables in both braquial biceps and right anterior tibial muscles (p < 0.05) in DMD patients. In LGMD we only found differences in a/t in braquial biceps. In MD the differences were observed in a/t, ratio and RSM in braquial biceps, and in a/t (in anterior tibial).

CONCLUSIONS

All the DMD patients show differences in IPA values in relation to control group, MD only in biceps, However there were not important changes in LGMD probably because the diversity and lack of homogeneity in affected muscles in this group.

摘要

引言

传统肌电图有助于区分神经肌肉疾病中的肌病和神经病模式,然而,与肌病变化相关的经典模式可能会导致神经源性成分,这种混淆可能是由于这些疾病不同阶段涉及的失神经和再支配变化。

目的

证明定量肌电图技术,如干扰模式分析(IPA),对于更好地区分肌肉营养不良症的重要性。

患者和方法

对95例患有3种不同肌肉营养不良症的患者进行了IPA:52例杜氏肌营养不良症(DMD)、33例肢带型肌营养不良症(LGMD)和10例强直性肌营养不良症(MD)患者,以及25例个体组成的对照组。评估了左侧肱二头肌和右侧胫前肌;分析的变量为转数/秒(t/s)、幅度/转数(a/t)、转数/平均幅度比和均方根(RSM)。

结果

我们发现,DMD患者的肱二头肌和右侧胫前肌的所有变量均存在统计学显著差异(p < 0.05)。在LGMD中,我们仅发现肱二头肌的a/t存在差异。在MD中,肱二头肌的a/t、比率和RSM以及胫前肌的a/t存在差异。

结论

所有DMD患者的IPA值与对照组相比均有差异,MD仅在二头肌中有差异,然而LGMD中没有重要变化,可能是因为该组受影响肌肉的多样性和缺乏同质性。

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