Jones R T, Squillace D L, Yunginger J W
Department of Pediatrics Mayo Clinic and Foundation, Rochester, Minnesota.
Ann Allergy. 1992 Mar;68(3):223-7.
Milk-allergic persons often rely on kosher labeling to select dairy-free foods. A 2-year-old boy experienced multiple generalized reactions after ingestion of milk or milk products; his serum contained elevated levels of milk-specific IgE antibodies, and his milk skin test was strongly positive. An identical reaction occurred after ingestion of "pareve"-labeled raspberry sorbet. Using an inhibition immunoassay with pooled sera from two milk-sensitive persons as the source of IgE antibodies, we found the milk allergen level in sorbet provided by the family to be 11% of the level found in non-fat dry milk. The milk allergen level in three independently purchased containers of sorbet ranged from 2% to undetectable. The presence of milk in three of four of the sorbets was confirmed by immunoblotting studies, by quantitation of milk proteins by polyacrylamide gel electrophoresis, and by quantitation of lactose by gas chromatography. Subsequently, it was discovered that milk was incorporated into the sorbet when equipment used to package ice cream had been used to package the sorbet. Although kosher labeling may provide assurance to milk-sensitive persons that a particular food does or does not contain milk, such labeling is no guarantee that this is indeed the case.
牛奶过敏者通常依靠犹太洁食标签来选择不含乳制品的食物。一名2岁男孩在摄入牛奶或奶制品后出现多次全身性反应；他的血清中牛奶特异性IgE抗体水平升高，并且他的牛奶皮肤试验呈强阳性。在摄入贴有“pareve”标签的树莓冰沙后也出现了相同的反应。我们以两名牛奶敏感者的混合血清作为IgE抗体来源，采用抑制免疫测定法，发现该家庭提供的冰沙中牛奶过敏原水平为脱脂奶粉中牛奶过敏原水平的11%。在独立购买的三盒冰沙中，牛奶过敏原水平在2%至检测不到之间。通过免疫印迹研究、聚丙烯酰胺凝胶电泳对牛奶蛋白进行定量以及气相色谱法对乳糖进行定量，证实了四盒冰沙中有三盒含有牛奶。随后发现，用于包装冰淇淋的设备被用于包装冰沙时，牛奶混入了冰沙中。尽管犹太洁食标签可能会让牛奶敏感者确信某种特定食物是否含有牛奶，但这种标签并不能保证实际情况确实如此。
