Loqman M Y, Wong C M, Hair-Bejo M, Zuki A B Z, Hafeez Y M
Faculty of Veterinary Medicine, Universiti Putra Malaysia.
Med J Malaysia. 2004 May;59 Suppl B:113-4.
A study was conducted to investigate the effectiveness of freeze-dried bovine pericardium (FDBP) as a biomaterial in diaphragmatic herniorrhapy in dogs. Eight adult dogs were randomly selected and divided into two equal groups. In FDBP group, a diaphragmatic defect was induced and repaired with an identical size of FDBP. In the control group, a diaphragmatic wall was incised at three-side border creating a flap and sutured. Grossly, only mild intrathoracic adhesion was observed for most of the animals, and no herniation occured. Microscopically, the biomaterial incorporated into the host's tissue by ingrowth of young muscle fiber and massive new blood vessel formation in between the fibrous tissue.
进行了一项研究，以调查冻干牛心包（FDBP）作为生物材料在犬膈疝修补术中的有效性。随机选择8只成年犬，将其平均分为两组。在FDBP组中，制造一个膈缺损并用相同大小的FDBP进行修复。在对照组中，在膈壁的三边交界处切开形成一个皮瓣并进行缝合。大体观察，大多数动物仅观察到轻度胸腔内粘连，未发生疝形成。显微镜下，生物材料通过年轻肌纤维长入以及纤维组织间大量新血管形成而融入宿主组织。
