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戊二醛保存的异种心包用于修复膈肌缺损:实验研究

Glutaraldehyde-preserved heterologous pericardium for the repair of diaphragmatic defects: experimental study.

作者信息

Gallo J I, Artiñano E, Val F, Duran C G

出版信息

J Thorac Cardiovasc Surg. 1982 Jun;83(6):905-8.

PMID:7087518
Abstract

Glutaraldehyde-treated porcine and bovine pericardium was used to close diaphragmatic defects in 15 dogs. The animals were reoperated upon between 15 days and 15 months. There were no adherences between the heterologous patch and the adjacent structures in any dogs except one, in which the omentum was attached to the pericardium. Microscopically, the graft structure remained intact without cellular invasion. The graft was covered with a thin layer of fibrous tissue, more intense in the one case of omental adhesions. There were no macroscopic or microscopic differences detectable in the behavior of the bovine and porcine pericardium. Although the follow-up is relatively short, these materials appear to offer a valid nonadherent alternative for diaphragmatic repair.

摘要

用戊二醛处理过的猪和牛心包膜用于闭合15只狗的膈肌缺损。这些动物在15天至15个月之间接受再次手术。除了一只网膜附着于心包膜的狗之外,在任何狗身上,异种补片与相邻结构之间均未出现粘连。显微镜下,移植结构保持完整,无细胞侵入。移植片覆盖有一层薄的纤维组织,在网膜粘连的一例中更为明显。在牛心包膜和猪心包膜的表现上,未发现宏观或微观差异。尽管随访时间相对较短,但这些材料似乎为膈肌修复提供了一种有效的无粘连替代物。

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