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八九十岁老人的颈动脉内膜切除术:值得为之努力吗?

Carotid endarterectomy in octogenarians and nonagenarians : is it worth the effort?

作者信息

Hingorani A, Ascher E, Schutzer R, Tsemkhim B, Kallakuri S, Yorkovich W, Jacob T

机构信息

Division of Vascular Surgery, Department of Surgery, Maimonides Medical Center, Brooklyn, New York 11219, USA.

出版信息

Acta Chir Belg. 2004 Aug;104(4):384-7.

Abstract

PURPOSE

The safety, effectiveness and cost issues of carotid endarterectomy (CEA) in the elderly patient have been debated due to the limited life expectancy and presumably increased rate of complications. This is despite multiple reports in the literature of excellent results in this population. To further examine this issue, we compared characteristics of three populations who underwent CEA at our institution: 53-79 year old patients (youngest group), 80-89 years old patients (middle group), and 90-98 year old patients (oldest group).

METHODS

Medical and financial data were obtained by retrospective review of hospital charts and billing records. We analyzed 266 random CEAs performed in 251 patients in the youngest group, 280 CEAs performed in 247 patients in the middle group and 19 CEA in 16 patients in the oldest group performed between 2/1/90 and 2/5/01.

RESULTS

Comparing each CEA group, there were no differences in gender (males: 56% vs. 51% vs. 53%), incidence of preoperative symptoms (43% vs. 43% vs. 42%), hypertension (68% vs. 60% vs. 42%), combined perioperative death and stroke rate (1.8% vs. 2.1% vs. 10%) or other complications (11% vs. 10% vs. 10%). Significant differences (p<0.05) were noted between the groups in incidence of diabetes (33% vs. 51% vs. 5% in each group), and heart disease (28% vs. 38% vs. 21%). Length of stay for admissions for CEA only were also similar in all three groups (2.37 days vs. 2.67 days vs. 2.36 days). A cost analysis of the earliest 230 patients in the entire series examining hospital cost per case revealed similar data for the < 80 years old and > 80 year old patients ($7,842 vs. $9,400).

CONCLUSIONS

Carotid endarterectomy can be performed in the elderly as safely and cost effectively as in the younger population.

摘要

目的

由于预期寿命有限且并发症发生率可能增加,老年患者颈动脉内膜切除术(CEA)的安全性、有效性和成本问题一直存在争议。尽管文献中有多篇报道称该人群手术效果良好。为了进一步研究这个问题,我们比较了在我们机构接受CEA手术的三组人群的特征:53 - 79岁患者(最年轻组)、80 - 89岁患者(中间组)和90 - 98岁患者(最年长组)。

方法

通过回顾医院病历和计费记录获取医疗和财务数据。我们分析了1990年2月1日至2001年2月5日期间在最年轻组251例患者中进行的266例随机CEA手术、中间组247例患者中进行的280例CEA手术以及最年长组16例患者中进行的19例CEA手术。

结果

比较每组CEA手术,性别(男性:56%对51%对53%)、术前症状发生率(43%对43%对42%)、高血压(68%对60%对42%)、围手术期死亡和中风合并发生率(1.8%对2.1%对10%)或其他并发症(11%对10%对10%)均无差异。各组间糖尿病发生率(每组分别为33%对51%对5%)和心脏病发生率(28%对38%对21%)存在显著差异(p<0.05)。仅CEA手术入院的住院时间在所有三组中也相似(2.37天对2.67天对2.36天)。对整个系列中最早的230例患者进行的每例病例医院成本的成本分析显示,<80岁和>80岁患者的数据相似(7842美元对9400美元)。

结论

老年患者进行颈动脉内膜切除术与年轻人群一样安全且具有成本效益。

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