Defieber Christian, Paquin Jean-François, Serna Sonia, Carreira Erick M
Laboratorium für Organische Chemie, ETH Hönggerberg, HCI H335, 8093 Zürich, Switzerland.
Org Lett. 2004 Oct 14;6(21):3873-6. doi: 10.1021/ol048240x.
[reaction: see text] We document a series of investigations that led to new substituted [2.2.2]-diene ligands which display high selectivity in Rh(I)-catalyzed conjugate addition reactions to substrates not previously examined with diene ligands. Moreover, we disclose an unexpected, interesting effect that results from the introduction of a third C=C onto the ligand scaffold (cf. 1).
[反应：见正文] 我们记录了一系列研究，这些研究产生了新的取代的[2.2.2]-二烯配体，它们在铑(I)催化的对以前未用二烯配体研究过的底物的共轭加成反应中表现出高选择性。此外，我们还揭示了由于在配体骨架上引入第三个碳-碳双键而产生的一种意想不到的有趣效应（参见1）。
