Stothard J R, Lockyer A E, Kabatereine N B, Tukahebwa E M, Kazibwe F, Rollinson D, Fenwick A
Schistosomiasis Control Initiative, Department of Infectious Diseases Epidemiology, Imperial College, London, UK.
J Helminthol. 2004 Sep;78(3):281-4. doi: 10.1079/joh2004239.
During routine parasitological surveillance and monitoring activities within a National Control Programme for control of human schistosomiasis in Uganda, it was noted that cattle grazing in a water meadow immediately adjacent to Tonya primary school, where the prevalence of intestinal schistosomiasis in children was in excess of 90%, were unusually emaciated. To test the hypothesis that there may have been an anthropozoonotic focus of Schistosoma mansoni within the local herd, a young female heifer, clearly emaciated and c. 8 months old, was slaughtered from which schistosome worms were later recovered by dissection. As female worms inspected by microscopy were not gravid, morphological identification proved inconclusive but analysis of cytochrome oxidase subunit I (COI) and small subunit (SSU) ribosomal DNA sequences from these worms identified them as Schistosoma bovis Sonsino, 1876. This is the first substantiated report of S. bovis from Lake Albert, western Uganda. Further epidemiological surveys are needed to clarify the extent of bovine schistosomiasis within this region, particularly so since this lakeside plain has been earmarked as a future game reserve.
在乌干达全国人体血吸虫病控制规划开展的常规寄生虫学监测活动中，注意到在托尼亚小学紧邻的水草甸放牧的牛异常消瘦，而该校儿童肠道血吸虫病患病率超过90%。为检验当地牛群中可能存在曼氏血吸虫人兽共患病疫源地这一假说，宰杀了一头明显消瘦、约8月龄的年轻雌性小母牛，随后通过解剖从中检出了血吸虫。由于显微镜检查的雌虫未成熟，形态学鉴定结果不明确，但对这些虫体的细胞色素氧化酶亚基I（COI）和小亚基（SSU）核糖体DNA序列分析确定它们为1876年发现的牛血吸虫。这是乌干达西部艾伯特湖牛血吸虫的首个实证报告。需要进一步开展流行病学调查，以明确该地区牛血吸虫病的流行程度，特别是因为这片湖滨平原已被指定为未来的野生动物保护区。
