Schiavon F, Circhetta C, Dani L
Reumatismo. 2004 Jul-Sep;56(3):139-42. doi: 10.4081/reumatismo.2004.139.
Diabetes mellitus is a chronic metabolic condition characterized by persistent hyperglycaemia with resultant morbidity and mortality related to its microvascular and macrovascular complications. In addition diabetes is also associated with several musculoskeletal disorders of the hand, that can be debilitating. There is increased incidence of these abnormalities in patients with type 1 and type 2 diabetes compared with the general population, related to disease duration but not to the age or sex. Typical diabetes associated hand condition include the palmar flexor tenosynovitis, Dupuytren's contracture, syndrome of limited joint mobility, carpal tunnel syndrome, Charcot arthropathy and reflex sympathetic dystrophy. Maintaining good glycaemic control by exercise, diet and drugs improves or prevents the development of these hand rheumatic condition. In this brief report we review the rational therapeutic approach to these disorders.
糖尿病是一种慢性代谢性疾病,其特征为持续性高血糖,并伴有因微血管和大血管并发症导致的发病和死亡。此外,糖尿病还与手部的几种肌肉骨骼疾病相关,这些疾病可能使人衰弱。与普通人群相比,1型和2型糖尿病患者中这些异常情况的发生率更高,这与病程有关,而与年龄或性别无关。典型的糖尿病相关手部疾病包括掌侧屈肌腱鞘炎、杜普伊特伦挛缩症、关节活动受限综合征、腕管综合征、夏科关节病和反射性交感神经营养不良。通过运动、饮食和药物维持良好的血糖控制可改善或预防这些手部风湿性疾病的发生。在本简要报告中,我们回顾了针对这些疾病的合理治疗方法。