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内收型痉挛性发声障碍的Ⅱ型甲状软骨成形术的长期效果

Long-term results of type II thyroplasty for adductor spasmodic dysphonia.

作者信息

Chan Sor Way, Baxter Malcolm, Oates Jenni, Yorston Anne

机构信息

Royal Victorian Eye and Ear Hospital, Melbourne, Australia.

出版信息

Laryngoscope. 2004 Sep;114(9):1604-8. doi: 10.1097/00005537-200409000-00019.

DOI:10.1097/00005537-200409000-00019
PMID:15475790
Abstract

OBJECTIVES

To assess the outcome of type II thyroplasty in the treatment of adductor spasmodic dysphonia (ASD).

STUDY DESIGN

Prospective case series.

METHODS

Thirteen patients with the diagnosis of ASD who were previously treated successfully with botulinum toxin therapy were recruited. Type II thyroplasty as described by Nobuhiko Isshiki was performed on all the patients. A self-rating assessment of the degree of severity and vocal effort were recorded and compared preoperatively and during postoperative follow-up.

RESULTS

There were four early failures in our series, with two caused by friable thyroid cartilage. In the early postoperative period, after excluding the early failures, six (66.7%) and seven (77.8%) patients had moderate-good improvement in symptom severity and vocal effort, respectively. During the follow-up period, a further five patients had deterioration of voice quality and were classified as failures. Of these five patients, two patients had reversal of their procedure. At the end of the follow-up period (mean follow-up period of 12 months), six (66.7%) and five (55.5%) patients sustained improvement in symptom severity and vocal effort, respectively. However, only two (22.2%) and three (33.3%) patients had moderate-good improvements in symptom severity and vocal effort, respectively, after 12 months.

CONCLUSIONS

Botulinum toxin injection remains the gold-standard treatment for ASD in our center. Potential patients for type II thyroplasty need to be carefully selected and counseled by a multidisciplinary team of otolaryngologists, neurologists, and speech pathologists.

摘要

目的

评估Ⅱ型甲状成形术治疗内收型痉挛性发声障碍(ASD)的疗效。

研究设计

前瞻性病例系列研究。

方法

招募13例先前接受肉毒杆菌毒素治疗成功的ASD患者。对所有患者均实施如Nobuhiko Isshiki所描述的Ⅱ型甲状成形术。记录并比较术前及术后随访期间患者自我评估的严重程度及发声用力程度。

结果

本系列中有4例早期失败病例,其中2例是由于甲状腺软骨易碎所致。在术后早期,排除早期失败病例后,分别有6例(66.7%)和7例(77.8%)患者的症状严重程度及发声用力程度有中度至良好改善。在随访期间,另有5例患者声音质量恶化,被归类为失败病例。在这5例患者中,有2例接受了手术逆转。在随访期末(平均随访期12个月),分别有6例(66.7%)和5例(55.5%)患者的症状严重程度及发声用力程度持续改善。然而,12个月后,分别仅有2例(22.2%)和3例(33.3%)患者的症状严重程度及发声用力程度有中度至良好改善。

结论

在本中心,肉毒杆菌毒素注射仍是ASD的金标准治疗方法。Ⅱ型甲状成形术的潜在患者需要由耳鼻喉科医生、神经科医生和言语病理学家组成的多学科团队进行仔细筛选和咨询。

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