巴西东北部伯南布哥州人群中13个STR基因座的遗传分析。
Genetic analysis of 13 STR loci in the population from the State of Pernambuco, northeast Brazil.
作者信息
Dellalibera Edileine, Havro Michele Lucy Bezerra, Souza Marcela, Kajihara Kazuo, Mauricio-da-Silva Luiz, dos Santos Silva Rosilda
机构信息
Department of Genetics, Biological Sciences Center, Federal University of Pernambuco, Avenue Professor Moraes Rego, S/N, Cidade Universitária, 50732-970 Recife PE, Brazil.
出版信息
Forensic Sci Int. 2004 Nov 10;146(1):57-9. doi: 10.1016/j.forsciint.2004.04.005.
Allele frequencies for 13 short tandem repeats (STR) loci obtained from a sample of 546 unrelated individuals from the State of Pernambuco, northeast Brazil, were studied. This population represents a trihybrid population composed of individuals presenting an admixture of Caucasian, African, and Native American. In the present study, the distributions of the genotypes in the evaluated loci CSF1PO, TH01, TPOX, F13A1, FESFPS, vWA, D16S539, D7S820, D13S317, D18S51, D21S11, D8S1179, FGA are in Hardy-Weinberg equilibrium. These loci were studied together with the Amel locus to perform the CODIS systems used in the USA. The calculated forensic parameters showed that the loci are useful for the solution of forensic problems in the Brazilian northeast region.
对从巴西东北部伯南布哥州546名无亲缘关系个体的样本中获得的13个短串联重复序列（STR）基因座的等位基因频率进行了研究。该人群是一个由具有高加索人、非洲人和美洲原住民混合血统个体组成的三杂种人群。在本研究中，评估的基因座CSF1PO、TH01、TPOX、F13A1、FESFPS、vWA、D16S539、D7S820、D13S317、D18S51、D21S11、D8S1179、FGA的基因型分布处于哈迪-温伯格平衡。这些基因座与Amel基因座一起进行研究，以执行美国使用的联合DNA索引系统（CODIS）。计算出的法医参数表明，这些基因座有助于解决巴西东北地区的法医问题。
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