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在巴西亚马逊地区的混合人群中,从 12 个 CODIS STR 基因座获得的等位基因频率和统计数据。

Allelic frequencies and statistical data obtained from 12 codis STR loci in an admixed population of the Brazilian Amazon.

机构信息

Laboratório de Genética Forense, Departamento de Laboratórios Forenses, Polícia Técnico-Científica do Amapá, Macapá, AM, Brazil.

出版信息

Genet Mol Biol. 2011 Jan;34(1):35-9. doi: 10.1590/S1415-47572011000100007. Epub 2011 Mar 1.

Abstract

The allelic frequencies of 12 short tandem repeat loci were obtained from a sample of 307 unrelated individuals living in Macapá, a city in the northern Amazon region, Brazil. These loci are the most commonly used in forensics and paternity testing. Based on the allele frequency obtained for the population of Macapá, we estimated an interethnic admixture for the three parental groups (European, Native American and African) of, respectively, 46%, 35% and 19%. Comparing these allele frequencies with those of other Brazilian populations and of the Iberian Peninsula population, no significant distances were observed. The interpopulation genetic distances (F(ST) coefficients) to the present database ranged from F(ST) = 0.0016 between Macapá and Belém to F(ST) = 0.0036 between Macapá and the Iberian Peninsula.

摘要

从生活在巴西亚马孙北部城市马卡帕的 307 名无关个体中获得了 12 个短串联重复序列基因座的等位基因频率。这些基因座是法医学和亲子鉴定中最常用的。基于马卡帕人群的等位基因频率,我们估计了三个父群体(欧洲人、美洲原住民和非洲人)的种族间混合程度,分别为 46%、35%和 19%。将这些等位基因频率与其他巴西人群和伊比利亚半岛人群的频率进行比较,没有观察到显著的差异。与本数据库的种群间遗传距离(F(ST)系数)范围从马卡帕和贝伦之间的 F(ST) = 0.0016 到马卡帕和伊比利亚半岛之间的 F(ST) = 0.0036。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d78/3085370/b70182647428/gmb-34-1-35-gfig1.jpg

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