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生物量暴露与高分辨率计算机断层扫描及肺功能检查结果

Biomass exposure and the high resolution computed tomographic and spirometric findings.

作者信息

Arslan Mubeccel, Akkurt Ibrahim, Egilmez Hulusi, Atalar Mehmet, Salk Ismail

机构信息

Department of Radiology, Faculty of Medicine, Cumhuriyet Universitesi, Tip Fakultesi Hastanesi, Radyoloji Anabilim Dali, 58140 Sivas, Turkey.

出版信息

Eur J Radiol. 2004 Nov;52(2):192-9. doi: 10.1016/j.ejrad.2004.01.011.

DOI:10.1016/j.ejrad.2004.01.011
PMID:15489079
Abstract

BACKGROUND

The adverse health effects of biomass fuel exposure (BFE) is complex and widespread. According to our knowledge, the interstitial lung disease due to BFE is not clear in literature.

OBJECTIVE

In this descriptive crossectional study, the main objective was to assess the effects of BFE on the respiratory system.

METHODS

Patient group was included non-smoker 21 woman and the control group was included non-smoker 22 woman. High resolution computed tomographic (HRCT) examinations were made with supin and prone positions in two groups. The spirometric measurements, including the diffusion capacity at rest for carbon monoxide, single breath (DLCO), were also made.

RESULTS

It was found that BFE caused obstructive and restrictive spirometric impairments. The prevalence of the fibrotic bands, peribronchovascular thickenings, nodular radio opacities, and curvilinear densities in the high resolution computed tomographic examinations were 7, 5, 7, and 16 times higher in the exposure group than the control group, respectively. There was a significant positive correlation between the forced vital capacity (FVC), forced expiratory volume first second (FEV(1)), FEV(1)/FVC, forced expiratory flow during middle half of forced vital capacity (FEF25-75), DLCO and the volumetric densities of the HRCT slices with deep expiration in prone position.

CONCLUSIONS

We think that, the findings due to BFE, pose a special situation and it can be named "biomass lung".

摘要

背景

接触生物质燃料(BFE)对健康的不良影响复杂且广泛。据我们所知,文献中关于BFE所致间质性肺病尚不明确。

目的

在这项描述性横断面研究中,主要目的是评估BFE对呼吸系统的影响。

方法

患者组纳入21名不吸烟女性,对照组纳入22名不吸烟女性。两组均在仰卧位和俯卧位进行高分辨率计算机断层扫描(HRCT)检查。还进行了包括静息一氧化碳弥散量、单次呼吸(DLCO)在内的肺功能测量。

结果

发现BFE导致了阻塞性和限制性肺功能损害。高分辨率计算机断层扫描检查中纤维化带、支气管血管周围增厚、结节状放射性opacity和曲线密度的患病率,暴露组分别比对照组高7、5、7和16倍。用力肺活量(FVC)、第一秒用力呼气量(FEV(1))、FEV(1)/FVC、用力肺活量中期用力呼气流量(FEF25 - 75)、DLCO与俯卧位深呼气时HRCT切片的体积密度之间存在显著正相关。

结论

我们认为,BFE所致的这些发现构成一种特殊情况,可称之为“生物质肺”。

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