Wu Tong, Kong De-Yun, Li Hui-Ting
Shanghai Institute of Pharmaceutical Industry, Shanghai 200040, China.
Yao Xue Xue Bao. 2004 Jul;39(7):525-7.
To study the bioactive components from Helicia nilagirica.
Compounds were separated with a combination of multi-chromatography. Their chemical structures were determined on the basis of spectral analysis and chemical evidence.
Two compounds were isolated from the leaves of Helicia nilagirica. Compound 1 was elucidated as 1-O-3-D-glucopyranosyl-(2S,3S,4R,8Z)-2-[(2'R)-2'-hyd roxylignocenoyl-amino]-8-octadecene-1, 3, 4-triol. Compound 2 was an analogue of 1.
The two compounds are new cerebrosides.
研究尼泊尔山龙眼的生物活性成分。
采用多种色谱联用的方法分离化合物。根据光谱分析和化学证据确定其化学结构。
从尼泊尔山龙眼叶中分离得到两种化合物。化合物1被鉴定为1-O-β-D-吡喃葡萄糖基-(2S,3S,4R,8Z)-2-[(2'R)-2'-羟基木脂酰氨基]-8-十八碳烯-1,3,4-三醇。化合物2是化合物1的类似物。
这两种化合物是新的脑苷脂。
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