Florindo Alex Antonio, Latorre Maria do Rosario Dias de Oliveira, Santos Elisabete Cristina Morandi dos, Borelli Aurélio, Rocha Manoel de Souza, Segurado Aluisio Augusto Cotrim
Departamento de Epidemiologia, Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, SP, Brazil.
Rev Saude Publica. 2004 Oct;38(5):643-9. doi: 10.1590/s0034-89102004000500005. Epub 2004 Oct 18.
To validate different methods for estimating HIV/Aids patients' body fat: total body skinfold thickness, central (trunk) skinfold thickness, peripheral (limb) skinfold thickness, waist circumference (WC) and waist-to-hip ratio (WHR). Dual-energy X-ray absorptiometry (DEXA) and computed tomography of the abdomen (CTA) were used as the gold standard.
An analysis was done on 15 adult HIV/Aids patients (10 men and 5 women) who were being treated at an Aids clinic at a public university hospital, Sao Paulo, Brazil. Their total subcutaneous fat (TSF) was estimated from the sum of the thicknesses of the biceps, triceps, subscapular, midaxillary, suprailiac, abdominal and medial calf skinfolds. The central subcutaneous fat (CSF) was estimated by summing the subscapular, axillary, suprailiac and abdominal skinfold measurements. The peripheral subcutaneous fat (PSF) was estimated by summing the biceps, triceps and medial calf skinfold measurements. These were compared with Dexa. The WC, WHR and CSF were compared with CTA. In the statistical analysis, the Pearson correlation coefficient (r) and Mann-Whitney test were utilized.
There was a correlation between fat mass measured by DEXA and by TSF, CSF and PSF, even after adjusting for age (r> or =0.80 for all). WC, WHR and CSF presented correlation with total abdominal fat measured by CTA, even after adjusting for age (r> or =0.80 for all).
The methods for estimating body fat should be chosen according to the type of fat to be evaluated and can be used in research and healthcare services instead of DEXA and CTA for HIV/AIDS patients.
验证用于估计艾滋病毒/艾滋病患者体脂的不同方法：全身皮褶厚度、中心（躯干）皮褶厚度、外周（肢体）皮褶厚度、腰围（WC）和腰臀比（WHR）。双能X线吸收法（DEXA）和腹部计算机断层扫描（CTA）被用作金标准。
对在巴西圣保罗一所公立大学医院的艾滋病诊所接受治疗的15名成年艾滋病毒/艾滋病患者（10名男性和5名女性）进行了分析。通过肱二头肌、肱三头肌、肩胛下、腋中、髂上、腹部和小腿内侧皮褶厚度之和来估计其总皮下脂肪（TSF）。通过将肩胛下、腋窝、髂上和腹部皮褶测量值相加来估计中心皮下脂肪（CSF）。通过将肱二头肌肱三头肌和小腿内侧皮褶测量值相加来估计外周皮下脂肪（PSF）。将这些与DEXA进行比较。将WC、WHR和CSF与CTA进行比较。在统计分析中，使用了Pearson相关系数（r）和Mann-Whitney检验。
即使在调整年龄后，DEXA测量的脂肪量与TSF、CSF和PSF测量的脂肪量之间仍存在相关性（所有r≥ 0.80）。即使在调整年龄后，WC、WHR和CSF与CTA测量的腹部总脂肪之间也存在相关性（所有r≥ 0.80）。
应根据要评估的脂肪类型选择估计体脂的方法，并且这些方法可用于艾滋病毒/艾滋病患者的研究和医疗服务中，以替代DEXA和CTA。
